Almex 400 mg (Chewable Tablet)

Unit Price: ৳ 5.02 (12 x 4: ৳ 240.96)

Strip Price: ৳ 20.08

Medicine Details

Category	Details
Generic	Albendazole
Company	Square pharmaceuticals plc
Also available as	Almex 200 mg suspension

Indications

Hookworm (Ancylostoma, Necator)
Roundworm (Ascaris)
Threadworm (Enterobius)
Whipworm (Trichuris)
Strongyloides
Tapeworm
Opisthorchi
Hydatid

Description

Almex is a benzimidazole anthelmintic, active against most nematodes and some cestodes. It is used in the treatment of intestinal nematode infections and in higher doses in the treatment of hydatid disease. Almex exhibits vermicidal, ovicidal, and larvicidal activity.

Pharmacology

Albendazole is a broad spectrum anthelmintic. Albendazole exhibits vermicidal, ovicidal and larvicidal activities. The drug is thought to exert its anthelmintic effect by blocking glucose uptake in the susceptible helminths, thereby depleting the energy level until it becomes inadequate for survival. Immobilization is followed by the parasite.

Dosage & Administration

Adults & children over 2 years: 400 mg (1 tablet or 10 ml suspension) as a single dose in cases of various infections.
Children of 1-2 years: Recommended dose is a single dose of 200 mg (5 ml suspension).
Hydatid disease (Echinococcosis): Albendazole is given in different doses for patients based on their weight and type of Echinococcosis.

Interaction

No interaction involving Almex, either pharmacodynamic or pharmacokinetic, has been reported.

Contraindications

Neonates
Children
Pregnant women
Concurrent disease: No evidence to suggest that dose should be altered in renal, hepatic or cardiac failure.

Side Effects

Gastrointestinal disturbances
Headache
Dizziness
Changes in liver enzymes
Reversible alopecia
Rash
Fever
Blood disorders including leucopenia and pancytopenia
Allergic shock if cyst leakage
Convulsion and meningism in cerebral disease

Pregnancy & Lactation

US FDA Pregnancy category of Albendazole is C. So, Albendazole should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.

Precautions & Warnings

Blood counts and liver function tests before treatment and twice during each cycle; breastfeeding; exclude pregnancy before starting treatment. Almex should only be used in the treatment of Echinococcosis if there is constant medical supervision with regular monitoring of serum-transaminase concentrations and of leucocyte and platelet counts

Therapeutic Class

Anthelmintic

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children.