Veridom 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Veritas pharmaceuticals ltd |
Title
Veridom 10 mg Tablet
Categories
- Medicine
- Pharmacy
- Health & Wellness
Description
Veridom 10 mg Tablet is a dopamine antagonist medication used to treat nausea and vomiting, dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and for speeding barium transit in follow-through radiological studies.
ActiveIngredient
Domperidone
Brand
Veridom
DosageForm
Tablet
DosageStrength
10 mg
UsualAdultDose
10-20 mg (1-2 tablets or 10-20 ml suspension) every 6-8 hours daily
MaxAdultDose
80 mg daily
UsualPediatricDose
2-4 ml suspension/10 kg body weight or 0.4-0.8 ml pediatric drops/10 kg body weight every 6-8 hours daily
Administration
Should be taken 15-30 minutes before meals and, if necessary, before retiring
Pharmacology
Domperidone is a dopamine antagonist that blocks the dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and stomach, restoring normal motility and tone of the upper gastrointestinal tract.
Interaction
Concomitant administration of anticholinergic drugs may antagonize the antidyspeptic effect of domperidone. Antacids and antisecretory drugs should not be given simultaneously with domperidone as they lower its oral bioavailability. The main metabolic pathway of domperidone is through CYP3A4.
Contraindications
Domperidone is contraindicated in patients with known hypersensitivity to the drug, neonates, gastrointestinal hemorrhage, mechanical obstruction or perforation, and patients with prolactin releasing pituitary tumor (prolactinoma).
SideEffects
Rare side effects include transient intestinal cramps, extrapyramidal phenomena, hyperprolactinemia, and rare allergic reactions such as rash and urticaria.
PregnancyAndLactation
Domperidone should only be used during the first trimester of pregnancy if justified by the anticipated therapeutic benefit. It is excreted in breast milk but with lower concentrations than in plasma. Nursing is not recommended unless the expected benefits outweigh any potential risk.
PrecautionsAndWarnings
Should be used with absolute caution in children due to increased risk of extrapyramidal reactions. Should be used with caution in patients with hepatic impairment.
OverdoseEffects
Symptoms of overdosage may include drowsiness, disorientation, and extrapyramidal reactions, especially in children.
TherapeuticClass
Motility Stimulants, Dopamine Antagonist, Prokinetic drugs
StorageConditions
Store below 30°C, protected from light & moisture, keep out of children's reach
ChemicalStructure
- MolecularFormula: C22H24ClN5O2
- ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg
SpecialPopulations
- Infants: Should only be given with caution and under close medical supervision due to incomplete development of metabolic and blood-brain barrier functions.
- LiverDisorders: Should be used with caution in patients with hepatic impairment.
- KidneyDisorders: In patients with severe renal insufficiency, dosing frequency and dose may need to be reduced on repeated administration.
CommonQuestions
- What is Veridom 10 mg Tablet used for? - Veridom 10 mg Tablet is a dopamine antagonist medication which is used to treat nausea and vomiting.
- Quick Tips: Veridom 10 mg Tablet helps relieve nausea, vomiting, and indigestion.