Chuben DS 400 mg (Chewable Tablet)
Unit Price: ৳ 5.00 (12 x 4: ৳ 240.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Alco pharma ltd |
Title
- Chuben DS
Category
- Medicine
- Anthelmintic
Description
Chuben DS is a benzimidazole anthelmintic, active against most nematodes and some cestodes. It is used in the treatment of intestinal nematode infections and in higher doses in the treatment of hydatid disease. Chuben DS exhibits vermicidal, ovicidal, and larvicidal activity. The principal mode of action of Chuben DS is its inhibitory effect on tubulin polymerization, which results in the loss of cytoplasmic microtubules.
Indications
- Hookworm infestation
- Roundworm infestation
- Threadworm infestation
- Whipworm infestation
- Strongyloides infestation
- Tapeworm infestation
- Opisthorchi infestation
- Hydatid disease
Mode of Action
- Vermicidal activity
- Ovicidal activity
- Larvicidal activity
- Inhibitor of tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Blocks glucose uptake in helminths
- Depletes energy level in helminths
- Binds to parasite tubulin
- Extensively metabolized
- Poorly absorbed from gastrointestinal tract
Dosage & Administration
- Recommended dosage for adults and children over 2 years
- Recommended dosage for children of 1-2 years
- Dosage in hydatid disease for patients weighing over 60 kg
- Dosage in hydatid disease for patients weighing less than 60 kg
- Dosage in giardiasis
Interaction
- No reported pharmacodynamic interaction
- No reported pharmacokinetic interaction
Contraindications
- Not recommended for neonates
- Dose reduction in children weighing less than 10 kg
- Not recommended during pregnancy or in women thought to be pregnant
- No alteration in dose for renal, hepatic, or cardiac failure
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Reversible alopecia
- Rash
- Fever
- Blood disorders
- Allergic shock
- Convulsion and meningism
Pregnancy & Lactation
- US FDA Pregnancy category C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Blood counts and liver function tests before treatment
- Twice during each cycle
- Breastfeeding caution
- Exclude pregnancy before starting treatment
- Constant medical supervision during treatment of Echinococcosis
- Regular monitoring of serum-transaminase concentrations
- Regular monitoring of leucocyte and platelet counts
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children