Clavoxil 500 mg+125 mg (Tablet)

Unit Price: ৳ 25.00 (3 x 6: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Amoxicillin clavulanic acid
Company Renata limited
Also available as

Title

  • Co-amoxiclav

Categories

  • Antibiotics
  • Medication

Composition

Amoxicillin, Clavulanic Acid

Forms Available

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection

Color

Varies with specific product form

Indications

  • Upper Respiratory Tract Infections
  • Lower Respiratory Tract Infections
  • Genito-urinary Tract Infections
  • Skin and Soft Tissue Infections
  • Bone and Joint Infections
  • Other Infections

Mode of Action

Bactericidal activity against Gram-positive & Gram-negative microorganisms

Pharmacokinetic Properties

Peak serum levels one hour after oral administration

Dosage for Adults

  • 625 mg Tablet every 12 hours
  • 375 mg Tablet every 8 hours
  • 1 gm Tablet every 12 hours
  • 1 gm Injection every 8 hours

Dosage for Children

Varies by age and type of infection

Administration

  • Oral
  • IV Injection

Interaction

  • Prolongation of bleeding time
  • Reduction in efficacy of oral contraceptives
  • Concomitant use with allopurinol

Contraindications

  • Penicillin hypersensitivity
  • Previous history of Co-amoxiclav or Penicillin-associated cholestatic jaundice

Side Effects

  • Diarrhoea
  • Nausea
  • Vomiting
  • Hepatitis
  • Urticarial and erythematous rashes
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

Not recommended in pregnancy unless considered essential by the physician

Precautions & Warnings

  • Patients on anticoagulation therapy
  • Severe hepatic dysfunction
  • Moderate or severe renal impairment

Use in Special Populations

  • Dose adjustment for renal impairment
  • Monitoring hepatic function in hepatic impairment

Overdose Effects

  • Unlikely to occur
  • Gastrointestinal symptoms
  • Disturbance of fluid and electrolyte balances

Therapeutic Class

Broad spectrum penicillins

Reconstitution

IV injection reconstituted in Water for Injection BP

Storage Conditions

  • Below 25°C
  • Protected from light and moisture
  • Refrigeration for reconstituted suspension
  • Limited usage duration for reconstituted vial

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