Epa 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.50 (3 x 10: ৳ 195.00)
Strip Price: ৳ 65.00

Medicine Details

Category Details
Generic Esomeprazole
Company Zenith pharmaceuticals ltd
Also available as
Epa 20 mg tablet

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Treatment of acid-related dyspepsia
  • Treatment of duodenal and gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Inhibition of H+/K+-ATPase in gastric parietal cell
  • Enteric-coated pellet formulation
  • Absorption peak at approximately 1.5 hours
  • Extensively metabolized by liver enzymes
  • Plasma protein binding of 97%
  • Metabolism by cytochrome P450 enzyme system
  • Plasma elimination half-life of approximately 1–1.5 hours

Dosage

  • Oral dosage form
  • IV injection or infusion
  • Different dosages for specific indications
  • Appropriate dosages for pediatric and adult patients
  • Specific instructions for administration

Administration

  • Tablet or capsule should be swallowed whole
  • Oral suspension administration
  • IV injection preparation and administration

Interaction

  • Metabolism by CYP2C19 and CYP3A4 enzymes
  • Potential interference with absorption of certain drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion in milk not studied
  • Breastfeeding discontinuation if essential

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Specific instructions for patients with swallowing difficulties

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed in elderly individuals
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • No alteration of pharmacokinetics in patients with renal impairment

Overdose Effects

  • Signs of acute toxicity in animal studies
  • No specific antidote known
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions about Epa 20 mg Capsule

  • Description of Epa 20 mg Capsule
  • Uses of Epa 20 mg Capsule
  • Common side effects of Epa 20 mg Capsule
  • Use of Epa 20 mg Capsule during pregnancy and breastfeeding
  • Time to onset of action for Epa 20 mg Capsule
  • Quick tips for taking Epa 20 mg Capsule

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