Dolopen 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 45.00 (7's pack: ৳ 315.00)

Medicine Details

Indications

  • Gram-positive infections
  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Enteritis
  • Endocarditis
  • Urinary tract infection
  • Meningitis
  • Septicaemia
  • Prophylactic use in surgery

Pharmacology

  • Active against Gram-positive organisms
  • Little activity against Gram-negative bacilli
  • Inhibits cell wall formation
  • Bactericidal
  • Peptidoglycan synthesis inhibition
  • Resists action of bacterial penicillinase

Dosage

  • Oral administration
  • Parenteral administration
  • Dosage for adults and children
  • Dosage adjustment for severe infections

Administration

  • Oral administration 1 hour before meal

Interaction

  • Concurrent use may result in increased levels in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Dyspepsia
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Excretion in human milk
  • Caution in lactating mothers

Precautions & Warnings

  • Caution in hepatic dysfunction patients
  • Caution in allergic patients

Use in Special Populations

  • Caution in severe renal failure

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Used in other routes
  • Intraarticular injection
  • Intrapleural injection
  • Inhaled by nebuliser

Storage Conditions

  • Keep in dry place
  • Away from light and heat
  • Keep out of reach of children

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