Flubac 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 95.00

Medicine Details

Indications

  • Treatment of skin and soft tissue infections
  • Treatment of respiratory tract infections
  • Treatment of osteomyelitis
  • Treatment of enteritis
  • Treatment of endocarditis
  • Prophylactic use during major surgical procedures

Pharmacology

  • Active against Gram-positive organisms
  • Inhibits the formation of cell wall of bacteria
  • Bactericidal antibiotic
  • Resistance to hydrolysis by penicillinase
  • Activity against penicillinase-producing staphylococci

Dosage

  • Oral administration for adults: 250 mg four times daily
  • Oral administration for children (2-10 years): Half of adult dose
  • Parenteral administration for adults: 250 mg four times daily
  • Parenteral administration for children (2-10 years): Half of adult dose

Administration

Oral doses should be administered 1 hour before meal

Interaction

Concurrent use may result in increased level of Flucloxacillin in blood for prolonged period

Contraindications

Contraindicated in penicillin hypersensitive patients

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • No adequate and well-controlled studies in pregnant women
  • Caution should be exercised when administered to a lactating mother

Precautions & Warnings

  • Use with caution in patients with evidence of hepatic dysfunction
  • Caution should be exercised in the treatment of patients with an allergic diathesis

Use in Special Populations

In severe renal failure, a reduction in dose should be considered

Therapeutic Class

Penicillinase-resistant penicillins

Reconstitution

Administered in other routes in conjunction with systemic therapy

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children

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