Flupen 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 65.00

Medicine Details

Indications

  • Treats skin and soft tissue infections
  • Treats respiratory tract infections
  • Used in osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia
  • Prophylactic agent for major surgical procedures

Pharmacology

  • Active against Gram-positive organisms
  • Little activity against Gram-negative bacilli
  • Inhibits formation of cell wall of bacteria
  • Bactericidal antibiotic
  • Kills bacterial cell wall by interfering with peptidoglycan synthesis

Dosage

  • Oral administration for adults, children (2-10 years), and children under 2 years
  • Parenteral administration for adults, elderly, and children

Administration

  • Oral doses should be administered 1 hour before meal

Interaction

  • Concurrent use may result in increased level of Flupen in blood for prolonged period

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Common gastrointestinal side effects such as nausea, vomiting, diarrhoea
  • Rashes, urticaria, purpura, fever, interstitial nephritis, hepatitis, cholestatic jaundice

Pregnancy & Lactation

  • Category B in pregnancy
  • Excreted in human milk, caution in lactating mothers

Precautions & Warnings

  • Use with caution in patients with evidence of hepatic dysfunction
  • Caution in patients with allergic diathesis

Use in Special Populations

  • Reduction in dose or extension of dose interval in severe renal failure

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Used in other routes in conjunction with systemic therapy
  • Administered in intraarticular and intrapleural injection
  • Dissolved in sterile water and inhaled by nebuliser

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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