Perpen 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 60.18

Medicine Details

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Enteritis
  • Endocarditis
  • Urinary tract infection
  • Meningitis
  • Septicaemia
  • Prophylactic agent for surgical procedures

Pharmacology

  • Active against Gram-positive organisms
  • Inhibits formation of bacteria cell wall
  • Bactericidal antibiotic
  • Useful against penicillinase-producing staphylococci

Dosage

  • Oral administration
  • Parenteral administration
  • Dosage for adults
  • Dosage for children
  • Intramuscular injection
  • Intravenous injection
  • Administered 1 hour before meal

Administration

  • Oral doses should be administered 1 hour before meal

Interaction

  • Concurrent use may result in increased level of Perpen in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Gastrointestinal side effects
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Caution in use during pregnancy and lactation

Precautions & Warnings

  • Use with caution in patients with hepatic dysfunction
  • Caution in treatment of patients with allergic diathesis

Use in Special Populations

  • Reduce dose or extend dose interval in severe renal failure

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Use in other routes in conjunction with systemic therapy
  • Administered by intraarticular injection
  • Administered by intrapleural injection
  • Administered by nebuliser

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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