Phylopen 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Indications

  • Treatment of skin and soft tissue infections
  • Treatment of respiratory tract infections
  • Used for osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia
  • Prophylactic agent for major surgical procedures

Pharmacology

  • Active against Gram-positive organisms including penicillinase producing strains
  • Inhibits the formation of bacterial cell wall
  • Resistance to hydrolysis by penicillinase
  • Bactericidal against penicillinase-producing staphylococci

Dosage

  • Oral administration for adults: 250 mg four times daily
  • Oral administration for children (2-10 years): half of adult dose
  • Parenteral administration for adults: 250 mg-1 g four times daily

Administration

  • Oral doses administered 1 hour before meal

Interaction

  • Concurrent use may result in increased level of Phylopen in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side effects

  • Common side effects of gastrointestinal tract such as nausea, vomiting, diarrhea
  • Rashes, urticaria, fever, interstitial nephritis, hepatitis reported

Pregnancy lactation

  • Pregnancy Category B
  • Excreted in human milk, caution needed during lactation

Precautions warnings

  • Use with caution in patients with evidence of hepatic dysfunction
  • Caution in treatment of patients with allergic diathesis

Special populations

  • Consider dose reduction in severe renal failure

Therapeutic class

  • Penicillinase-resistant penicillins

Reconstitution

  • Administered in other routes in conjunction with systemic therapy
  • Administered by intraarticular and intrapleural injection
  • Inhaled by nebulizer

Storage conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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