Skilox 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 65.00

Medicine Details

Indications

  • Treatment of Gram-positive organisms infections
  • Skin and soft tissue infections treatment
  • Respiratory tract infections treatment
  • Osteomyelitis treatment
  • Enteritis treatment
  • Endocarditis treatment
  • Urinary tract infection treatment
  • Meningitis treatment
  • Prophylactic agent for major surgical procedures

Pharmacology

  • Active against Gram-positive organisms
  • Little activity against Gram-negative bacilli
  • Bactericidal antibiotic
  • Inhibits formation of bacterial cell wall
  • Resists action of bacterial penicillinase
  • Interferes with peptidoglycan synthesis

Dosage

  • 250mg oral dose for adults
  • 1/2 adult dose for children (2-10 years)
  • 1/4 adult dose for children (under 2 years)
  • Up to 8g daily for severe infections
  • Parenteral administration for adults and children

Administration

  • Oral doses administered 1 hour before meal

Interaction

  • Concurrent use may increase Skilox levels in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Common gastrointestinal side effects
  • Nausea
  • Vomiting
  • Diarrhoea
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Caution advised during lactation

Precautions & Warnings

  • Use with caution in hepatic dysfunction patients
  • Caution in allergic diathesis

Use in Special Populations

  • Caution in severe renal failure

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Used in other routes with systemic therapy
  • Administered by intraarticular injection
  • Administered by intrapleural injection
  • Administered by inhalation using nebulizer

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of reach of children

Related Brands