Cefot 500 mg/10 ml (IM/IV Injection)
500 mg vial: ৳ 76.23
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefotaxime |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of septicaemia
- Treatment of respiratory tract infections
- Treatment of urinary tract infections
- Treatment of soft-tissue infections
- Treatment of bone and joint infections
- Treatment of obstetric and gynaecological infections
- Treatment of gonorrhoea
- Prophylactic administration to reduce postoperative infections
Pharmacology
- Binds to penicillin binding proteins
- Inhibits peptidoglycan synthesis
- Broad spectrum bactericidal action
- Active against gram-negative organisms
- Activity against gram-positive bacteria
Dosage & Administration
- Adult dosage of 1 gm every 12 hours
- Increased dosage for severe infections
- Children's dosage range
- Neonates dosage range
- Dosage for gonorrhoea
Interaction
- Increased nephrotoxicity with aminoglycoside antibiotics
Contraindications
- Hypersensitivity to cefotaxime or cephalosporin antibiotics
Side Effects
- Candidiasis
- Rashes
- Fever
- Transient rises in liver transaminase
- Diarrhoea
- Pseudomembranous colitis
- Renal function changes
- Hypersensitivity reactions
Pregnancy & Lactation
- Careful consideration in pregnancy
- Excretion in breast milk
Precautions & Warnings
- Caution in individuals with gastrointestinal disease
- Dosage reduction in patients with renal insufficiency
- No need for dosage adjustment in patients with profound renal dysfunction
Use in Special Populations
- Dosage adjustment in severe renal failure
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store below 25°C
- Protect from light and moisture
- Use reconstituted solution immediately
- Stability of reconstituted solution