Cefotax 250 mg/5 ml (IM/IV Injection)

250 mg vial: ৳ 75.00

Medicine Details

Indications

  • Septicaemia
  • Respiratory Tract Infections
  • Urinary Tract Infections
  • Soft-tissue Infection
  • Bone and Joint Infections
  • Obstetric and gynaecological infections
  • Gonorrhoea
  • Prophylaxis

Pharmacology

  • Binds to penicillin binding proteins
  • Inhibits peptidoglycan synthesis
  • Bactericidal
  • Broad spectrum
  • Active against gram-negative organisms
  • Activity against gram-positive bacteria

Dosage & Administration

  • Recommended dosage for adults
  • Recommended dosage for children
  • Recommended dosage for neonates
  • Dosage in gonorrhoea

Interaction

  • Increased nephrotoxicity with aminoglycoside antibiotics

Contraindications

  • Hypersensitivity to cefotaxime or cephalosporin group of antibiotics

Side Effects

  • Candidiasis
  • Rashes
  • Fever
  • Transient rises in liver transaminase and/or alkaline phosphatase
  • Diarrhoea
  • Pseudomembranous colitis
  • Changes in renal function
  • Hypersensitivity reactions

Pregnancy & Lactation

  • Studies in animals
  • Excretion in milk

Precautions & Warnings

  • Prescribed with caution in individuals with a history of gastrointestinal disease
  • Reduction of urinary output in patients with renal insufficiency
  • Dosage adjustment in severe renal failure
  • Necessity of changing the dosage in patients with renal dysfunction

Use in Special Populations

  • Dosage in renal impairment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store below 25°C
  • Protected from light and moisture
  • Reconstituted solution stability

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