Cefotax 1 gm/10 ml (IM/IV Injection)

1 gm vial: ৳ 180.00

Medicine Details

Indications

  • Septicaemia
  • Respiratory Tract Infections
  • Urinary Tract Infections
  • Soft-tissue Infection
  • Bone and Joint Infections
  • Obstetric and gynaecological infections
  • Gonorrhoea
  • Parenteral antibiotic therapy

Pharmacology

Binds to penicillin binding proteins, broad spectrum bactericidal, active against gram-negative organisms, similar to other cephalosporins in activity against gram-positive bacteria

Dosage & Administration

  • Recommended dosage for adults
  • Recommended dosage for children
  • Recommended dosage for neonates
  • Dosage in gonorrhoea

Interaction

Increased nephrotoxicity with concomitant administration of cephalosporins and aminoglycoside antibiotics

Contraindications

Hypersensitivity to cefotaxime or cephalosporin group of antibiotics

Side Effects

  • Candidiasis
  • Rashes
  • Fever
  • Transient rises in liver transaminase and/or alkaline phosphatase
  • Diarrhoea
  • Pseudomembranous colitis
  • Changes in renal function
  • Hypersensitivity reactions

Pregnancy & Lactation

Unknown safety in human pregnancy, excreted in the milk

Precautions & Warnings

  • Prescribed with caution in individuals with a history of gastrointestinal disease
  • Reduction of dosage in patients with renal insufficiency

Use in Special Populations

Dosage reduction in severe renal failure, adjustment in all other patients according to the course of infection and general condition

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store below 25°C, protected from light and moisture, reconstituted solution stable for up to 24 h if stored between 2°C to 8°C

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