Cefotax 1 gm/10 ml (IM/IV Injection)

1 gm vial: ৳ 180.00

Medicine Details

Category	Details
Generic	Cefotaxime
Company	Renata limited
Also available as	Cefotax 250 mg injection Cefotax 500 mg injection

Indications

Septicaemia
Respiratory Tract Infections
Urinary Tract Infections
Soft-tissue Infection
Bone and Joint Infections
Obstetric and gynaecological infections
Gonorrhoea
Parenteral antibiotic therapy

Pharmacology

Binds to penicillin binding proteins, broad spectrum bactericidal, active against gram-negative organisms, similar to other cephalosporins in activity against gram-positive bacteria

Dosage & Administration

Recommended dosage for adults
Recommended dosage for children
Recommended dosage for neonates
Dosage in gonorrhoea

Interaction

Increased nephrotoxicity with concomitant administration of cephalosporins and aminoglycoside antibiotics

Contraindications

Hypersensitivity to cefotaxime or cephalosporin group of antibiotics

Side Effects

Candidiasis
Rashes
Fever
Transient rises in liver transaminase and/or alkaline phosphatase
Diarrhoea
Pseudomembranous colitis
Changes in renal function
Hypersensitivity reactions

Pregnancy & Lactation

Unknown safety in human pregnancy, excreted in the milk

Precautions & Warnings

Prescribed with caution in individuals with a history of gastrointestinal disease
Reduction of dosage in patients with renal insufficiency

Use in Special Populations

Dosage reduction in severe renal failure, adjustment in all other patients according to the course of infection and general condition

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store below 25°C, protected from light and moisture, reconstituted solution stable for up to 24 h if stored between 2°C to 8°C