Taxim 500 mg/10 ml (IM/IV Injection)
500 mg vial: ৳ 100.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefotaxime |
| Company | Acme laboratories ltd |
| Also available as |
Product Title and Categories
- Taxim - Cefotaxime Injection
- Antibiotic
- Third Generation Cephalosporins
Indications
- Septicaemia
- Respiratory Tract Infections
- Urinary Tract Infections
- Soft-tissue Infection
- Bone and Joint Infections
- Obstetric and gynaecological infections
- Gonorrhoea
- Bacterial Meningitis
- Infection Prophylaxis
Pharmacology
- Binds to penicillin binding proteins (PBPs)
- Inhibits transpeptidation step of peptidoglycan synthesis
- Bacterial cell wall inhibition
- Broad spectrum bactericidal action
- Active against gram-negative organisms
- Activity against gram-positive bacteria
Dosage & Administration
- Recommended dosage for adults: 1 gm every 12 hours
- Children dosage range: 100-150 mg/kg/day
- Neonates dosage: 50 mg/kg/day
- Dosage in gonorrhoea: 500 mg as a single dose
Interaction
- Increased nephrotoxicity with concomitant administration of cephalosporins and aminoglycoside antibiotics
Contraindications
- Hypersensitivity to cefotaxime or cephalosporin antibiotics
Side Effects
- Candidiasis
- Rashes
- Fever
- Transient liver enzyme rises
- Diarrhoea
- Pseudomembranous colitis
- Renal function changes
- Hypersensitivity reactions
Pregnancy & Lactation
- Safety not established in human pregnancy
- Excreted in milk
Precautions & Warnings
- Prescribed with caution in individuals with gastrointestinal disease
- Dosage reduction for patients with renal insufficiency
- No clinical evidence supporting dosage change in profound renal dysfunction
Use in Special Populations
- Dosage reduction in severe renal failure
- Further dosage adjustment according to infection and patient condition
Therapeutic Class
- Third generation cephalosporins
Storage Conditions
- Store below 25°C
- Protected from light and moisture
- Reconstituted solution stable for up to 24 hours if stored between 2°C to 8°C