Torped 250 mg/5 ml (IM/IV Injection)
250 mg vial: ৳ 50.35
Medicine Details
Category | Details |
---|---|
Generic | Cefotaxime |
Company | Orion pharma ltd |
Also available as |
Indications
- Treatment of septicaemia
- Treatment of respiratory tract infections
- Treatment of urinary tract infections
- Treatment of soft-tissue infections
- Treatment of bone and joint infections
- Treatment of obstetric and gynaecological infections
- Treatment of gonorrhoea
- Prophylactic use for reducing post-operative infections
Pharmacology
- Binds to penicillin binding proteins (PBPs)
- Inhibits final transpeptidation step of peptidoglycan synthesis
- Broad-spectrum bactericidal 3rd generation cephalosporin antibiotic
- Active against gram-negative organisms
- Active against gram-positive bacteria
Dosage & Administration
- Recommended dosage for adults
- Recommended dosage for children
- Recommended dosage for neonates
- Dosage for gonorrhoea
- Variation of dosage according to severity of infection and patient's condition
Interaction
- Increased nephrotoxicity with concomitant administration of cephalosporins and aminoglycoside antibiotics
Contraindications
- Hypersensitivity to cefotaxime or cephalosporin group of antibiotics
Side Effects
- Adverse reactions
- Candidiasis
- Rashes
- Fever
- Transient rises in liver transaminase and alkaline phosphatase
- Diarrhoea
- Pseudomembranous colitis
- Changes in renal function
- Hypersensitivity reactions
- Skin rashes
- Drug fever
- Anaphylaxis
Pregnancy & Lactation
- Safety in human pregnancy not established
- Excretion in milk
Precautions & Warnings
- Caution in individuals with history of gastrointestinal disease
- Caution in patients with transient or persistent reduction of urinary output
- Dosage reduction in patients with renal insufficiency
- No necessity of changing dosage in patients with profound renal dysfunction
Use in Special Populations
- Dosage adjustment in renal impairment
Therapeutic Class
- Third generation cephalosporins
Storage Conditions
- Store below 25°C
- Protected from light and moisture
- Use reconstituted solution immediately
- Stability of reconstituted solution for up to 24 hours if stored between 2°C to 8°C
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