Torped 250 mg/5 ml (IM/IV Injection)

250 mg vial: ৳ 50.35

Medicine Details

Indications

  • Treatment of septicaemia
  • Treatment of respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of soft-tissue infections
  • Treatment of bone and joint infections
  • Treatment of obstetric and gynaecological infections
  • Treatment of gonorrhoea
  • Prophylactic use for reducing post-operative infections

Pharmacology

  • Binds to penicillin binding proteins (PBPs)
  • Inhibits final transpeptidation step of peptidoglycan synthesis
  • Broad-spectrum bactericidal 3rd generation cephalosporin antibiotic
  • Active against gram-negative organisms
  • Active against gram-positive bacteria

Dosage & Administration

  • Recommended dosage for adults
  • Recommended dosage for children
  • Recommended dosage for neonates
  • Dosage for gonorrhoea
  • Variation of dosage according to severity of infection and patient's condition

Interaction

  • Increased nephrotoxicity with concomitant administration of cephalosporins and aminoglycoside antibiotics

Contraindications

  • Hypersensitivity to cefotaxime or cephalosporin group of antibiotics

Side Effects

  • Adverse reactions
  • Candidiasis
  • Rashes
  • Fever
  • Transient rises in liver transaminase and alkaline phosphatase
  • Diarrhoea
  • Pseudomembranous colitis
  • Changes in renal function
  • Hypersensitivity reactions
  • Skin rashes
  • Drug fever
  • Anaphylaxis

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Excretion in milk

Precautions & Warnings

  • Caution in individuals with history of gastrointestinal disease
  • Caution in patients with transient or persistent reduction of urinary output
  • Dosage reduction in patients with renal insufficiency
  • No necessity of changing dosage in patients with profound renal dysfunction

Use in Special Populations

  • Dosage adjustment in renal impairment

Therapeutic Class

  • Third generation cephalosporins

Storage Conditions

  • Store below 25°C
  • Protected from light and moisture
  • Use reconstituted solution immediately
  • Stability of reconstituted solution for up to 24 hours if stored between 2°C to 8°C

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