Amlobet 5 mg+50 mg (Tablet)
Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atenolol |
| Company | Sun pharmaceutical bangladesh ltd |
Indications
- Essential hypertension
- Angina pectoris & hypertension as co-existing diseases
- Post myocardial infarction
- Refractory angina pectoris
Pharmacology
- Fixed-dose combination of Amlodipine and Atenolol
- Dihydropyridine calcium antagonist
- Peripheral vasodilator
- Reduction in peripheral vascular resistance
- Reduction in blood pressure
- Reduction in myocardial oxygen demand
- Cardioselective beta-blocker
- Reduction in cardiac output
Dosage & Administration
- Recommended dosage of Amlodipine and Atenolol 5/25 mg tablet once daily
- Dosage may be increased to 5/25 mg two tablets daily
- Dosage should be individualized
Interaction
- Atenolol reduces the clearance of disopyramide by 20%
- Additive negative inotropic effects of heart with disopyramide
- Ampicillin may reduce Atenolol levels
- Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Fatigue
- Headache
- Edema
- Nausea
- Drowsiness
- Anxiety
- Depression
Pregnancy & Lactation
- Use during pregnancy if expected benefit outweighs the potential fetal risk
- Not for use by nursing mothers
Precautions & Warnings
- Use with caution in patients with airway obstruction
- Use with caution in patients with renal impairment
- Use with caution in patients with severe liver damage
- Warn patients against sudden drug withdrawal
Overdose Effects
- Hypotension
- Congestive cardiac failure
- Unabsorbed drugs removal by gastric lavage or administration of activated charcoal
- Symptomatic treatment
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children