Camlodin Plus 5 mg+50 mg (Tablet)

Unit Price: ৳ 8.00 (4 x 14: ৳ 448.00)
Strip Price: ৳ 112.00

Medicine Details

Category Details
Generic Amlodipine besilate atenolol
Company Square pharmaceuticals plc
Also available as
Camlodin plus 5 mg tablet

Indications

  • Essential hypertension
  • Angina pectoris and hypertension as co-existing diseases
  • Post myocardial infarction
  • Refractory angina pectoris

Pharmacology

  • Fixed-dose combination of Amlodipine and Atenolol
  • Amlodipine: dihydropyridine calcium antagonist
  • Amlodipine: peripheral vasodilator
  • Atenolol: cardioselective beta-blocker
  • Atenolol: reduction in blood pressure and myocardial oxygen demand

Dosage & Administration

  • Recommended dosage: Amlodipine and Atenolol 5/25 mg tablet once daily
  • Dosage may be increased as advised by physicians

Interaction

  • Disopyramide: Atenolol reduces clearance, leading to additive negative inotropic effects
  • Ampicillin: may reduce Atenolol levels
  • Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion

Contraindications

  • Hypersensitivity to either component
  • Sinus bradycardia
  • Second and higher degrees of heart block
  • Cardiogenic shock
  • Hypotension
  • Congestive heart failure
  • Poor left ventricular function

Side Effects

  • Well tolerated
  • Side-effects include fatigue, headache, edema, nausea, drowsiness, anxiety, depression

Pregnancy & Lactation

  • Use during pregnancy if benefit outweighs potential fetal risk
  • Not recommended for nursing mothers

Precautions & Warnings

  • Bronchospasm: use with caution in patients with airway obstruction
  • Renal impairment: caution if creatinine clearance is less than 30 ml/min
  • Hepatic impairment: caution in severe liver damage
  • Drug withdrawal: gradual discontinuation and under observation

Overdose Effects

  • Hypotension
  • Congestive cardiac failure
  • Unabsorbed drugs may be removed by gastric lavage or activated charcoal

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Keep below 30°C temperature
  • Away from light and moisture
  • Keep out of the reach of children

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