Amoclav (1 gm+200 mg)/20 ml (IV Injection)

1.2 gm vial: ৳ 300.00

Medicine Details

Category Details
Generic Amoxicillin clavulanic acid
Company Techno drugs ltd
Also available as
Amoclav 875 mg tablet Amoclav 125 mg suspension Amoclav 500 mg tablet Amoclav forte 400 mg suspension

Indications

  • Short-term treatment of upper respiratory tract infections
  • Short-term treatment of lower respiratory tract infections
  • Short-term treatment of genito-urinary tract infections
  • Short-term treatment of skin and soft tissue infections
  • Short-term treatment of bone and joint infections
  • Short-term treatment of other infections

Composition

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection

Pharmacology

  • Broad spectrum bactericidal activity
  • Pharmacokinetic properties matching

Dosage

  • Usual adult dose for 625 mg Tablet
  • Usual adult dose for 375 mg Tablet
  • Usual adult dose for 1 gm Tablet
  • Usual adult dose for Suspension
  • Usual adult dose for Forte suspension
  • Usual recommended daily dosage for mild to moderate infections
  • Usual recommended daily dosage for serious infections
  • Dosage for children
  • IV Injection dosage for adults
  • IV Injection dosage for children

Administration

  • Oral dosage form
  • IV injection administration

Interaction

  • Prolongation of bleeding time
  • Reduction of efficacy of oral contraceptives
  • Concomitant use with allopurinol

Contraindications

  • History of Penicillin hypersensitivity
  • Cross-sensitivity with other beta-lactam antibiotics
  • History of cholestatic jaundice

Side Effects

  • Diarrhoea
  • Pseudomembranous colitis
  • Indigestion
  • Nausea
  • Vomiting
  • Candidiasis
  • Hepatitis
  • Cholestatic jaundice
  • Urticarial and erythematous rashes
  • Erythema multiforme
  • Stevens-Johnson Syndrome
  • Exfoliative dermatitis
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

  • Animal studies showing no teratogenic effect
  • Limited use in human pregnancy
  • Detection in breast milk during lactation

Precautions & Warnings

  • Use in patients on anticoagulation therapy
  • Use in patients with severe hepatic dysfunction
  • Adjust dosage in patients with renal impairment
  • Maintenance of adequate fluid intake and urinary output

Use in Special Populations

  • Dosage adjustment for patients with renal impairment
  • Dose adjustment for patients with hepatic impairment

Overdose Effects

  • Gastrointestinal symptoms
  • Disturbance of fluid and electrolyte balances
  • Potential removal by haemodialysis

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • Reconstitution of IV injection
  • Incompatible reconstitution or mixtures

Storage Conditions

  • Storage temperature
  • Protection from light and moisture
  • Refrigeration of reconstituted suspension
  • Timeline for reconstituted vial usage

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