Amoclav (125 mg+31.25 mg)/5 ml (Powder for Suspension)
100 ml bottle: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin clavulanic acid |
| Company | Techno drugs ltd |
| Also available as |
Title
- Co-amoxiclav
Categories
- Antibacterial
- Antibiotic
- Medication
Description
- Short-term treatment of bacterial infections at various sites
- Available in multiple formulations and dosages
Dimensions
Color options
Functions
- Treats upper respiratory tract infections
- Treats lower respiratory tract infections
- Treats genito-urinary tract infections
- Treats skin and soft tissue infections
- Treats bone and joint infections
- Effective against a wide range of microorganisms
Materials
Technical specifications
- Film coated tablet formulations
- Powder for suspension formulations
- Injection formulations
Design elements
Usability features
- Oral dosage form
- Intravenous administration
- Reconstitution of IV injection
Dosage
- Specific dosages for adults and children over 12 years
- Different dosages for different types and severities of infections
- Dosage adjustments for patients with renal impairment
- Instructions for suspension dosage based on age and weight of children
Administration
- Oral administration with or without meals
- Intravenous administration over 2 minutes or slow infusion over 30 minutes
- Optimized absorption at the start of a meal
- Discarding unused reconstituted vial contents after 20 minutes
Interaction
- Potential interaction with anticoagulation therapy
- Possible reduction in oral contraceptives efficacy
Contraindications
- Contraindicated for individuals with history of penicillin hypersensitivity
- Cross-sensitivity with other beta-lactam antibiotics
- Contraindicated for patients with history of Co-amoxiclav or Penicillin-associated cholestatic jaundice
Side effects
- Uncommon side effects similar to those of Amoxicillin
- Mild and transitory nature of side effects
- Instructions for reducing gastrointestinal side effects
Pregnancy and lactation
- Limited data on the use of Co-amoxiclav during pregnancy
- Caution advised during lactation due to detection of trace quantities in breast milk
Precautions and warnings
- Caution advised in patients on anticoagulation therapy
- Dosage adjustments for patients with moderate or severe hepatic dysfunction
- Maintenance of adequate fluid intake and urinary output during high dose administration
Special population usage
- Dosage adjustments for patients with renal impairment
- Similar dosage reduction for children with renal impairment
- Caution and regular monitoring in hepatic impairment
Overdose effects
- Unlikelihood of overdose problems
- Possible gastrointestinal symptoms and electrolyte disturbances
- Potential removal of Co-amoxiclav by haemodialysis
Therapeutic class
- Broad spectrum penicillins
Reconstitution
- Reconstitution process for IV injection
- Incompatibility with specific solutions for reconstitution or mixing
Storage conditions
- Storage temperature below 25°C
- Protection from light and moisture
- Refrigeration of reconstituted suspension
- Limited shelf life of reconstituted vial
Composition
- 375 mg tablet
- 625 mg tablet
- 1 gm tablet
- Powder for Suspension
- Powder for Suspension (Forte)
- 1.2 gm Injection
- 0.6 gm injection
Pharmacology
- Antibacterial combination of Amoxicillin and Clavulanic Acid
- Pharmacokinetic properties closely matched
- Peak serum levels one hour after oral administration
- Optimized absorption at the start of a meal
Indications
- Treatment of bacterial infections at various sites
Interaction details
- Prolongation of bleeding time and prothrombin time reported in some patients
- Possible reduction in the efficacy of oral contraceptives
Contraindications details
- History of penicillin hypersensitivity
- Potential cross-sensitivity with other beta-lactam antibiotics
- Contraindication for patients with history of Co-amoxiclav or penicillin-associated cholestatic jaundice