Tyclav (500 mg+100 mg)/10 ml (IV Injection)

600 mg vial: ৳ 150.00

Medicine Details

Category Details
Generic Amoxicillin clavulanic acid
Company Beximco pharmaceuticals ltd
Also available as
Tyclav 125 mg suspension Tyclav 1 gm injection Tyclav 875 mg tablet Tyclav 250 mg tablet Tyclav 500 mg tablet Tyclav bid 400 mg suspension

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Genito-urinary tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Other infections

Dosage

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection

Composition

  • Amoxicillin 250 mg as Amoxicillin Trihydrate BP and Clavulanic Acid 125 mg as Diluted Potassium Clavulanate BP
  • Amoxicillin 500 mg as Amoxicillin Trihydrate BP and Clavulanic Acid 125 mg as Diluted Potassium Clavulanate BP
  • Amoxicillin 875 mg as Amoxicillin Trihydrate BP and Clavulanic Acid 125 mg Diluted Potassium Clavulanate BP
  • Amoxicillin 125 mg as Amoxicillin Trihydrate BP and Clavulanic Acid 31.25 mg as Diluted Potassium Clavulanate BP

Mode of Action

Broad spectrum of bactericidal activity against many Gram-positive & Gram-negative microorganisms

Usability

  • Oral administration
  • IV injection

Interaction

  • Prolongation of bleeding time and prothrombin time
  • Reduction of efficacy of oral contraceptives

Contraindications

  • History of Penicillin hypersensitivity
  • Cross-sensitivity with other beta-lactam antibiotics

Side Effects

  • Diarrhoea
  • Indigestion
  • Nausea
  • Vomiting
  • Hepatitis
  • Cholestatic jaundice
  • Urticarial and erythematous rashes
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

Not recommended unless considered essential by the physician

Precautions & Warnings

  • Care in patients on anticoagulation therapy
  • Dosage adjustment in patients with severe hepatic dysfunction
  • Adequate fluid intake and urinary output for high doses

Use in Special Populations

  • Dose adjustment for renal impairment
  • Monitoring hepatic function at regular intervals

Overdose Effects

  • Gastrointestinal symptoms
  • Fluid and electrolyte balance disturbance

Therapeutic Class

Broad spectrum penicillins

Reconstitution

Dissolving the powder in Water for Injection BP

Storage Conditions

  • Below 25°C
  • Refrigeration of reconstituted suspension
  • Reconstitution must be used within 20 minutes

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