Ampimet DS 125 mg/5 ml (Oral Suspension)
100 ml bottle: ৳ 43.75
Medicine Details
| Category | Details |
|---|---|
| Generic | Ampicillin sodium |
| Company | Medimet pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections of the genitourinary tract
- Treatment of respiratory tract infections
- Treatment of gastrointestinal tract infections
- Treatment of meningitis
- Bacteriology studies for causative organisms
- Therapy initiation prior to susceptibility testing results
Pharmacology
- Inhibition of bacterial cell wall synthesis
- Binding to penicillin-binding proteins
- Inhibition of transpeptidation step
- Lysis of bacteria
- Arrest of cell wall assembly
Dosage
- Intra-articular dosage for adults
- Intra-articular dosage for children
- Intraperitoneal dosage for adults
- Intraperitoneal dosage for children
- Intrapleural dosage for adults
- Intrapleural dosage for children
- Intravenous dosage for meningitis in adults
- Intravenous dosage for meningitis in children
- Intrapartum prophylaxis dosage for adults
- Oral dosage for various infections in adults and children
- Parenteral dosage for susceptible infections in adults
- Parenteral dosage for septicaemia in adults
- Parenteral dosage for septicaemia in children
Administration
Should be taken on an empty stomach
Interaction
- Reduced efficacy of oral contraceptives
- Alteration of INR while on warfarin and phenindione
- Reduced efficacy of oral typhoid vaccines
- Reduced excretion of methotrexate
- Reduced absorption with chloroquine
- Interference with bactericidal action by bacteriostatic antibacterials
Contraindications
Hypersensitivity to ampicillin and other penicillins
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Rashes
- Sore mouth
- Rash
- Fever
- Joint pains
- Haemolytic anaemia
- Thrombocytopenia
- Leucopenia
- CNS toxicity
- Nephropathy
- Hepatitis
- Anaphylaxis
Pregnancy & Lactation
Category B
Precautions & Warnings
- History of β-lactam allergy
- Renal impairment
- Pregnancy
- Lactation
Use in Special Populations
Dose reduction or increase in dose interval for patients with CrCl<10
Overdose Effects
- Symptoms: Nausea, vomiting, and diarrhoea
- Management: Symptomatic and supportive treatment
- Management: Removal from circulation by haemodialysis
Reconstitution
- Intramuscular reconstitution process
- Intravenous reconstitution process
- Intra-articular reconstitution process
- Intraperitoneal reconstitution process
- Intrapleural reconstitution process
Storage Conditions
Store between 20-25°C