Motigen 5 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 28.08
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Novo healthcare and pharma ltd |
| Also available as |
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Symptoms
- Epigastric sense of fullness
- Abdominal distention
- Upper abdominal pain
- Eructation
- Flatulence
- Early satiety
- Nausea
- Vomiting
- Heartburn
- Regurgitation of gastric contents
Pharmacology
- Dopamine antagonist
- Gastroprokinetic action
- Gastrointestinal motility
- Gastric emptying
- Peristalsis regulation
- Esophageal peristalsis
- Lower esophageal sphincter pressure
Dosage & Administration
- Recommended before meals
- Adult dose: 10-20 mg every 6-8 hours
- Children dose: 2-4 ml suspension/10 kg body weight
- Rectal administration for adults and children
- Maximum daily dose: 80 mg
Interactions
- Anticholinergic drug antagonism
- Antacids interference
- Metabolic pathway through CYP3A4
- Inhibition by azole antifungals
- Dopaminergic agonists interaction
Contraindications
- Hypersensitivity
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction
- Perforation
- Prolactin releasing pituitary tumor
Side Effects
- Intestinal cramps
- Extrapyramidal phenomena
- Prolactin increase
- Galactorrhoea
- Gynaecomastia
- Neurological side effects
Pregnancy & Lactation
- Safety during pregnancy
- Excretion in breast milk
- Advice for nursing mothers
Precautions & Warnings
- Caution in children
- Risk of extrapyramidal reactions
- Hepatic impairment caution
Special Populations
- Use in infants
- Liver disorders caution
- Kidney disorders caution
Overdose Effects
- Drowsiness
- Disorientation
- Activated charcoal treatment
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Temperature below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions
- Uses of Motigen 5 mg/5 ml Suspension
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