Cosec 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.05 (6 x 7: ৳ 338.10)

Strip Price: ৳ 56.35

Medicine Details

Category	Details
Generic	Omeprazole
Company	Drug international ltd
Also available as	Cosec 20 mg capsule Cosec 40 mg injection

Gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

20 mg once daily for benign gastric and duodenal ulcer
20 mg once daily for NSAID-associated duodenal or gastric ulcer
20 mg once daily for gastro-esophageal reflux disease
10-20 mg daily for long-term management of acid reflux disease
10-20 mg once daily for acid-related dyspepsia
40 mg on the preceding evening, then 40 mg 2-6 hours before surgery for prophylaxis of acid aspiration
Initially 60 mg once daily for Zollinger-Ellison syndrome
20 mg twice daily for Helicobacter pylori eradication regimen in peptic ulcer disease
10-20 mg once daily for 4-12 weeks in severe ulcerating reflux esophagitis (Child>1 year)

IV Injection for prophylaxis of acid aspiration, duodenal ulcer, gastric ulcer or reflux esophagitis
IV Infusion for prophylaxis of acid aspiration
Slow intravenous injection for IV Injection
Intravenous infusion over a period of 20-30 minutes or more for IV Infusion
Use within 4 hours of reconstitution for IV Injection
Use within 12 hours when Omeprazole is dissolved in saline and within 6 hours when dissolved in 5% Dextrose for IV Infusion

Decreased intragastric acidity may reduce the absorption of ketoconazole
Metabolised in the liver through cytochrome P450, can delay the elimination of diazepam, phenytoin, and warfarin
Monitoring of patients receiving warfarin or pheytoin is recommended
Plasma concentrations of Omeprazole and clarithromycin are increased during concomitant administration
No evidence of an interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxycillin or antacids

Skin rash, urticaria, and pruritus
Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia
Diarrhoea and headache
Constipation, nausea/vomiting, flatulence, and abdominal pain
Dry mouth, stomatitis, and candidiasis
Paraesthesia
Dizziness, light headedness, and feeling faint
Somnolence, insomnia, and vertigo
Reversible mental confusion, agitation, depression, and hallucinations
Arthritic and myalgic symptoms
Blurred vision, taste disturbance, peripheral oedema, increased sweating, gynaecomastia, leucopenia, thrombocytopenia, agranulocytosis, pancytopenia, anaphylactic shock, malaise, fever, bronchospasm, encephalopathy, hepatitis, interstitial nephritis, hepatic failure, increases in liver enzymes

No adverse effects on pregnancy or the health of the fetus/newborn child
Omeprazole can be used during pregnancy
No information available on the passage of Omeprazole into breast milk or its effects on the neonate

Avoid concomitant use of clopidogrel
Observational studies suggest an increased risk for osteoporosis-related fractures with PPI therapy
Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with Omeprazole
Concomitant use of PPIs with methotrexate may lead to methotrexate toxicities