OPmax 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.00 (10 x 10: ৳ 600.00)

Strip Price: ৳ 60.00

Medicine Details

Category	Details
Generic	Omeprazole
Company	Concord pharmaceuticals ltd
Also available as	Opmax 40 mg capsule

Gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

Substituted benzimidazole
Inhibitor of gastric acid secretion
Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
Onset of the antisecretory effect occurs within one hour
Maximum effect occurs within two hours
Inhibition of secretion lasts up to 72 hours
Secretory activity returns gradually over 3 to 5 days when the drug is discontinued

Oral administration
Benign gastric and duodenal ulcer: 20 mg once daily for 4 weeks in duodenal ulceration, 8 weeks in gastric ulceration
NSAID-associated duodenal or gastric ulcer: 20 mg once daily for 4 weeks, continued for further 4 weeks if not fully healed
Gastro-esophageal reflux disease: 20 mg once daily for 4 weeks, continued for further 4-8 weeks if not fully healed
Long-term management of acid reflux disease: 10-20 mg daily
Prophylaxis of acid aspiration: 40 mg on the preceding evening, then 40 mg 2-6 hours before surgery
Zollinger-Ellison syndrome: Initially 60 mg once daily; usual range 20-120 mg daily
IV Injection for various indications

Decreased intragastric acidity may reduce absorption of ketoconazole during OPmax treatment
OPmax is metabolized in the liver through cytochrome P450
Potential interactions with diazepam, phenytoin, warfarin, ketoconazole, clarithromycin, digoxin, methotrexate

Known hypersensitivity to omeprazole
Suspicion of gastric ulcer should exclude the possibility of malignancy before treatment is instituted

Mild and reversible adverse reactions
Skin rash, urticaria, and pruritus
Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia
Diarrhea, headache
Constipation, nausea/vomiting, flatulence, abdominal pain
Dry mouth, stomatitis, candidiasis
Paraesthesia
Dizziness, light-headedness, feeling faint
Somnolence, insomnia, vertigo
Reversible mental confusion, agitation, depression, hallucinations
Arthritic and myalgic symptoms
Blurred vision, taste disturbance, peripheral edema, increased sweating
Hepatic and hematological effects

No adverse effects reported on pregnancy or fetus/newborn child
Use during pregnancy is considered safe
No information available on the passage of omeprazole into breast milk
Breastfeeding should be discontinued if omeprazole use is considered essential
Safety and effectiveness not established in pediatric patients less than 18 years of age