Sectil 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.00 (100's pack: ৳ 500.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Cosmic pharma ltd |
| Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect occurs within one hour
- Maximum antisecretory effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
- Return of secretory activity gradually over 3 to 5 days after discontinuation
Dosage
- Recommended dosage for gastric and duodenal ulcer
- Recommended dosage for NSAID-associated duodenal or gastric ulcer
- Recommended dosage for gastro-esophageal reflux disease
- Recommended dosage for long-term management of acid reflux disease
- Recommended dosage for acid-related dyspepsia
- Recommended dosage for prophylaxis of acid aspiration
- Recommended dosage for Zollinger-Ellison syndrome
- Recommended paeditaric dosage for severe ulcerating reflux esophagitis
- Recommended IV injection dosage for various conditions
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
- Preparation of IV injection solution
- Preparation of IV infusion solution
Interaction
- Impact on the absorption of ketoconazole
- Metabolism through cytochrome P450
- Potential impact on diazepam, phenytoin, and warfarin
- Impact on blood concentration of phenytoin and coagulation time with warfarin
- Plasma concentration changes during concomitant administration
- No interaction observed with certain medications
Contraindications
- Known hypersensitivity to Omeprazole
- Need for exclusion of malignancy before treatment
Side Effects
- Mild and reversible adverse reactions
- Reported skin reactions
- Reported gastrointestinal reactions
- Reported neurological and psychological reactions
- Reported musculoskeletal symptoms
- Reported miscellaneous adverse effects
Pregnancy & Lactation
- Results from prospective epidemiological studies
- Use of Omeprazole during pregnancy
- Effects on breast milk and neonate
- Discontinuation of breastfeeding
Precautions & Warnings
- Avoid concomitant use of clopidogrel and Omeprazole
- Potential association with increased osteoporosis-related fractures
- Atrophic gastritis noted in long-term use
- Potential interaction with methotrexate
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children