Alton 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Title

Alton 20 mg Tablet

Categories

  • Heartburn Relief
  • GERD Medication
  • Ulcer Treatment

Description

Alton 20 mg Tablet is indicated for the relief from chronic heartburn symptoms, healing of erosive esophagitis, maintenance of healing of erosive esophagitis, eradication of Helicobacter pylori infection, treatment of Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal ulcer, and gastric ulcer.

Dimensions

N/A

Color options

  • White

Functions

  • Reduction of gastric acid secretion
  • Relief from heartburn
  • Healing of erosive esophagitis
  • Eradication of H. pylori infection
  • Treatment of acid-related dyspepsia
  • Management of duodenal and gastric ulcers

Materials

N/A

Technical specifications

  • Absorption: Peak plasma levels occur at approximately 1.5 hours after oral administration
  • Distribution: 97% bound to plasma proteins
  • Metabolism: Extensively metabolized in the liver by the CYP enzyme system
  • Excretion: Less than 1% excreted in the urine

Design elements

Enteric-coated pellet formulation of esomeprazole magnesium

Usability features

  • Dosage Form:
    • Tablet
    • Capsule
    • Oral Suspension
    • IV Injection
    • IV Infusion
  • Administration: Swallowed whole one hour before a meal (tablet or capsule)

Precautions warnings

  • Symptomatic Response: Does not preclude the presence of gastric malignancy
  • Administration Tip: Capsules can be swallowed whole or opened and mixed with applesauce if swallowing is difficult
  • Antacids: May be used while taking Alton

Pharmacology

Suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell.

Interactions

  • Metabolizing Enzymes: Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Potential Interference: May interfere with absorption of drugs where gastric pH is an important determinant of bioavailability

Contraindications

  • Known hypersensitivity to any of the formulation

Side effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal Pain
  • Constipation
  • Dry Mouth

Pregnancy lactation

  • Pregnancy: No adequate and well-controlled studies in pregnant women; animal studies have revealed no teratogenic effects
  • Lactation: Excretion in milk not studied; breastfeeding should be discontinued if esomeprazole use is considered essential

Special populations

  • Pediatric Use: Safety and effectiveness not established
  • Geriatric Use: No overall differences in safety and efficacy observed
  • Hepatic Insufficiency: No dosage adjustment recommended for mild to moderate insufficiency
  • Renal Insufficiency: Pharmacokinetics not expected to be altered

Overdose effects

  • Signs: Reduced motor activity, changes in respiratory frequency, tremor, ataxia, intermittent clonic convulsions
  • Specific Antidote: None known; treatment should be symptomatic and supportive

Storage conditions

Store at a temperature not exceeding 30°C in a dry place; protect from light and moisture; keep out of reach of children

Chemical structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure: Image available

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