Esocon 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.50 (6 x 10: ৳ 570.00)
Strip Price: ৳ 95.00

Medicine Details

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Peak plasma levels at approximately 1.5 hours
  • Extensively metabolized in the liver
  • Systemic bioavailability is approximately 90%
  • Absorption is decreased by 33-53% after food intake

Dosage

  • 20 mg or 40 mg for healing of erosive esophagitis
  • 20 mg for maintenance of healing of erosive esophagitis
  • 20 mg for symptomatic GERD
  • Triple therapy for Helicobacter pylori eradication
  • 20-80 mg for Zollinger-Ellison Syndrome
  • 20-40 mg for acid-related Dyspepsia
  • 20 mg for duodenal ulcer, 20-40 mg for gastric ulcer
  • IV injection or IV infusion for specific cases

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral suspension should be prepared and taken accordingly
  • IV injection should be administered intravenously over a period of at least 3 minutes

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • Unlikely to inhibit certain CYP enzymes
  • Potential interference with absorption of specific drugs
  • Not showing clinically significant interactions with certain drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion in milk not studied
  • Breast-feeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response does not exclude presence of gastric malignancy
  • Specific instructions for patients with difficulty swallowing capsules
  • Antacids may be used while taking Esocon

Use in Special Populations

  • Safety and effectiveness not established in paediatric patients
  • No overall differences in safety and efficacy between the elderly and younger individuals
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in patients with renal impairment

Overdose Effects

  • Acute toxicity signs in animal studies
  • No specific antidote known
  • Expected to be extensively protein bound
  • Symptomatic and supportive treatment advised

Storage Conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure: Image available

Common Questions about Esocon 40 mg Capsule

  • Overview of Esocon 40 mg Capsule's functionality
  • Multiple uses including heartburn relief and GERD treatment
  • Common side effects like headaches, diarrhea, nausea, etc.
  • Recommendation regarding use during pregnancy or breastfeeding
  • Onset of action within a few hours
  • Quick tips and precautions for users

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