Esotid 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 6.50 (7 x 14: ৳ 637.00)
Strip Price: ৳ 91.00

Medicine Details

Category Details
Generic Esomeprazole
Company Opsonin pharma ltd
Also available as
Esotid 40 mg tablet Esotid 20 mg capsule Esotid 40 mg capsule Esotid 40 mg injection

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of Acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Specific inhibition of the H+/K+-ATPase
  • First single optical isomer of proton pump inhibitor
  • Enteric-coated pellet formulation
  • Metabolized in the liver by CYP enzymes

Dosage

  • 20 mg or 40 mg Once Daily for healing of erosive esophagitis
  • 20 mg Once Daily for maintenance
  • 20 mg Once Daily for symptomatic GERD
  • Triple Therapy for Helicobacter pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for Acid-related Dyspepsia
  • 20 mg once daily for 2-4 weeks for Duodenal ulcer
  • 20-40 mg once daily for 4-8 weeks for Gastric ulcer
  • IV Injection or IV infusion for specific cases

Administration

  • Tablet or capsule should be swallowed whole one hour before a meal
  • Oral Suspension should be taken with water and stirred well
  • IV Injection should be administered over a specific time period

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • Unlikely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
  • Possible interference with CYP2C19
  • May interfere with drug absorption where gastric pH is important

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion in milk not studied

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Specific information for patients regarding capsule administration

Use in Special Populations

  • No established safety and effectiveness for paediatric patients
  • No overall differences in safety and efficacy observed between the elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • No expected alteration in pharmacokinetics in patients with renal impairment

Overdose Effects

  • No specific reports of overdose
  • Symptomatic and supportive treatment recommended
  • Expected lethality in extreme doses

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions about Esotid 20 mg Tablet

  • Proton pump inhibitor reducing stomach acid production
  • Various uses including treatment of GERD, ulcers, and other conditions
  • Common side effects and precautions
  • No established effects for pregnancy and breastfeeding
  • Quick tips for usage

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