Exmart 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Mst pharma |
Title
Exmart 20 mg Tablet
Categories
- Medicine
- Health & Wellness
Description
Exmart 20 mg Tablet is a proton pump inhibitor used for treating gastrointestinal conditions such as GERD, duodenal ulcers, and Zollinger-Ellison Syndrome.
Dimensions
N/A
Color options
- White
Functions
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Relief from acid-related dyspepsia
- Healing of duodenal and gastric ulcers
Materials
N/A
Technical specifications
- Absorption: Peak plasma levels occur at approximately 1.5 hours after oral administration
- Distribution: Esomeprazole is 97% bound to plasma proteins
- Metabolism: Extensively metabolized in the liver by the cytochrome P450 enzyme system
- Excretion: Plasma elimination half-life of esomeprazole is approximately 1-1.5 hours, with less than 1% excreted in the urine
Design elements
Capsules should be swallowed whole; oral suspension and IV injection have specific administration instructions
Usability features
- Tablet or capsule should be taken at least one hour before a meal
- Antacids may be used while taking Exmart
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Treatment of acid-related dyspepsia
- Healing of duodenal and gastric ulcers
Pharmacology
Proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell
Dosage
- Oral Dosage Form:
- Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
- Maintenance of Healing of Erosive Esophagitis: 20 mg Once Daily
- Symptomatic GERD: 20 mg Once Daily for 4 Weeks
- Helicobacter Pylori Eradication: Esomeprazole 40 mg Once Daily for 10 days, Amoxicillin 1000 mg Twice Daily for 10 days, Clarithromycin 500 mg Twice Daily for 10 days
- Zollinger-Ellison Syndrome: 20-80 mg once daily
- Acid-related Dyspepsia: 20-40 mg once daily for 2-4 weeks
- Duodenal & Gastric Ulcers: 20 mg once daily for 2-8 weeks
- IV Injection or IV Infusion:
- GERD with Erosive Esophagitis (Adult Patients): 20 mg or 40 mg once daily
- GERD with Erosive Esophagitis (Pediatric Patients): 10 mg Once Daily (Body weight <55 kg), 20 mg Once Daily (Body Weight ≥55 kg)
- Risk Reduction of Rebleeding of Gastric or Duodenal Ulcers: 80 mg IV Infusion over 30 minutes, followed by a continuous infusion of 8 mg/h for 72 hours
Administration
- Tablet or capsule: Should be swallowed whole and taken one hour before a meal
- Oral Suspension: Specific mixing and administration instructions
- IV Injection: Preparation and administration instructions provided
Interaction
- Metabolism: Extensively metabolized in the liver by CYP2C19 and CYP3A4
- Potential Interactions:
- Inhibition of CYP2C19 and interference with the absorption of certain drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side effects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy lactation
No adequate and well-controlled studies in pregnant women; excretion in milk not studied; breastfeeding should be discontinued if essential
Precautions warnings
- Symptomatic response to therapy does not preclude the presence of gastric malignancy
- Specific patient information provided
- Antacids may be used while taking Exmart
Special populations
- Paediatric Use: Safety and effectiveness not established in paediatric patients
- Geriatric Use: No overall differences in safety and efficacy observed; greater sensitivity of some older individuals cannot be ruled out
- Hepatic Insufficiency: Dose adjustment recommended for severe hepatic insufficiency
- Renal Insufficiency: Pharmacokinetics not expected to be altered in patients with renal impairment
Overdose effects
Acute toxicity signs and supportive treatment
Storage conditions
Store at a temperature not exceeding 30°C in a dry place, protect from light and moisture, keep out of reach of children
Chemical structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure: Image provided
Common questions
- What is Exmart 20 mg Tablet?: Proton pump inhibitor used for treating gastrointestinal conditions
- What is Exmart 20 mg Tablet used for?: Relief from heartburn, GERD symptoms, and treatment of various gastrointestinal conditions
- What are the side effects of Exmart 20 mg Tablet?: Common side effects include headaches, diarrhea, nausea, and more
- Pregnant or breastfeeding use?: Talk to doctor about risks and benefits