Neptor 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 12.00 (4 x 10: ৳ 480.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Esomeprazole
Company Sandoz a novartis division
Also available as
Neptor 20 mg capsule

Title

  • Neptor 40 mg Capsule

Categories

  • Indications:
    • Relief from chronic heartburn symptoms and other symptoms associated with GERD
    • Healing of erosive esophagitis
    • Maintenance of healing of erosive esophagitis
    • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
    • Zollinger-Ellison Syndrome
    • Acid related Dyspepsia
    • Duodenal & Gastric ulcer
  • Pharmacology:
    • Proton pump inhibitor that suppresses gastric acid secretion
    • Enteric-coated pellet formulation of esomeprazole magnesium
    • Peak plasma levels occur at approximately 1.5 hours
    • Metabolized in the liver by the cytochrome P450 (CYP) enzyme system
    • Plasma elimination half-life of approximately 1-1.5 hours
  • Dosage:
    • For healing of erosive esophagitis: 20 mg or 40 mg once daily for 4-8 weeks
    • For maintenance of healing of erosive esophagitis: 20 mg once daily
    • Symptomatic GERD: 20 mg once daily for 4 weeks
    • Helicobacter Pylori eradication: Triple Therapy for 10 days
    • Zollinger-Ellison Syndrome: The dose is 20-80 mg once daily
    • Acid-related Dyspepsia: 20-40 mg once daily for 2-4 weeks
    • Administration through IV Injection or IV infusion for different patient groups
  • Administration:
    • Tablet or capsule should be swallowed whole and taken one hour before a meal
    • Oral suspension should be taken after mixing with water
  • Interaction:
    • Extensively metabolized in the liver by CYP2C19 and CYP3A4
    • No clinically significant interactions with specific drugs
  • Contraindications:
    • Contraindicated in patients with known hypersensitivity to any of the formulation
  • Side Effects:
    • Headache
    • Diarrhea
    • Nausea
    • Flatulence
    • Abdominal pain
    • Constipation
    • Dry mouth
  • Pregnancy & Lactation:
    • No adequate and well-controlled studies in pregnant women
    • Breastfeeding should be discontinued if the use of esomeprazole is considered essential
  • Precautions & Warnings:
    • Symptomatic response to therapy does not preclude the presence of gastric malignancy
    • Instructions for patients on how to take Neptor capsules
    • Usage of antacids while taking Neptor
  • Use in Special Populations:
    • Safety and effectiveness in pediatric patients have not been established
    • No overall differences in safety and efficacy between the elderly and younger individuals
    • No dosage adjustment is recommended for patients with mild to moderate hepatic insufficiency
    • No alteration expected in the pharmacokinetics in patients with renal impairment
  • Overdose Effects:
    • Toxicity signs in animal studies
    • No specific antidote known
    • Symptomatic and supportive treatment recommended
  • Storage Conditions:
    • Store at a temperature not exceeding 30°C in a dry place
    • Protect from light and moisture

Description

  • Chemical Structure:
    • Molecular Formula: C17H19N3O3S
    • Chemical Structure Image: URL
  • Commonly Asked Questions:
    • Neptor 40 mg Capsule:
      • Definition and usage
      • Types of side effects
      • Safety during pregnancy and breastfeeding
      • Time for Neptor to start working
      • Quick Tips for using Neptor 40 mg Capsule

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