Roxyzin 25 mg (Tablet)

Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00

Medicine Details

Indications

  • Symptomatic relief of anxiety and tension associated with psychoneurosis
  • Management of pruritus due to allergic conditions
  • Sedative when used as premedication and following general anesthesia

Pharmacology

  • Anxiolytic antihistamine of the piperazine class
  • H1 receptor antagonist
  • Primary skeletal muscle relaxation
  • Bronchodilator activity
  • Antihistaminic and analgesic effects
  • Rapid absorption from the gastrointestinal tract
  • Clinical effects usually noted within 15 to 30 minutes after oral administration

Dosage & Administration

  • Adults: 50-100 mg 4 times daily for anxiety and tension relief
  • Children (>6 years): 50-100 mg daily in divided doses for anxiety and tension relief
  • Adults: 25 mg 3 to 4 times daily for pruritus due to allergic conditions
  • Interaction with meperidine and barbiturates
  • No interference with the action of digitalis
  • Contraindicated in patients with known hypersensitivity to hydroxyzine or any of its ingredients

Side Effects

  • Mild and transitory side effects
  • Drowsiness
  • Headache
  • Psychomotor impairment
  • Antimuscarinic effects such as urinary retention, dry mouth, and blurred vision
  • Gastrointestinal disturbances
  • Rare side effects include hypotension, palpitation, arrhythmias, and liver dysfunction

Pregnancy & Lactation

  • Inadequate clinical data in early pregnancy
  • Contraindicated in early pregnancy
  • Unknown excretion in human milk

Precautions & Warnings

  • Potentiating action when used with CNS depressants
  • Drowsiness warning to patients
  • Caution against driving or operating machinery
  • Advised against simultaneous use of other CNS depressant drugs
  • Start with half the recommended dose in the elderly
  • Half of the normal dose in case of renal impairment

Overdose Effects

  • Manifestation of hypersedation
  • General supportive care and monitoring of vital signs
  • Possible intravenous fluids and specific pressor agents for hypotension
  • No specific antidote
  • Hemodialysis may be indicated with concomitant barbiturate ingestion

Therapeutic Class

  • Sedating antihistamine

Storage Conditions

  • Store in a cool & dry place
  • Protect from light
  • Keep out of the reach of children

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