Roxyzin 10 mg/5 ml (Syrup)

100 ml bottle: ৳ 40.00

Medicine Details

Indications

  • Symptomatic relief of anxiety and tension
  • Management of pruritus due to allergic conditions
  • Sedative for premedication and following general anesthesia

Pharmacology

  • Anxiolytic antihistamine
  • H1 receptor antagonist
  • Skeletal muscle relaxation
  • Bronchodilator activity
  • Analgesic effects
  • Antiemetic effect

Dosage & Administration

  • Adult dosage for anxiety and tension relief
  • Adult dosage for pruritus due to allergic conditions
  • Children dosage for anxiety and tension relief
  • Children dosage for pruritus due to allergic conditions
  • Dosage as a sedative for premedication and following general anesthesia

Interaction

  • Potentiation of Meperidine and barbiturates
  • No interference with the action of digitalis
  • Avoidance of simultaneous administration with monoamine oxidase inhibitors

Contraindications

  • Known hypersensitivity to Hydroxyzine or any ingredients

Side Effects

  • Drowsiness
  • Headache
  • Psychomotor impairment
  • Antimuscarinic effects
  • Urinary retention
  • Dry mouth
  • Blurred vision
  • Gastrointestinal disturbances
  • Rare side-effects like hypotension, palpitation, arrhythmias, extrapyramidal effects, dizziness, confusion, depression, sleep disturbances, tremor, convulsions, hypersensitivity reactions, blood disorders, liver dysfunction, angle-closure glaucoma

Pregnancy & Lactation

  • Contraindicated in early pregnancy
  • Unknown excretion in human milk

Precautions & Warnings

  • Potentiating action with central nervous system depressants
  • Caution against driving or operating machinery
  • Caution against simultaneous use of other CNS depressant drugs
  • Increased effect of alcohol

Use in Special Populations

  • Half dose for renal impairment patients
  • Start with half the recommended dose in the elderly

Overdose Effects

  • Hypersedation
  • Vomiting induction if not occurred spontaneously
  • Immediate gastric lavage recommended
  • General supportive care
  • Control hypotension with intravenous fluids
  • No specific antidote
  • Hemodialysis may be indicated if ingested concomitantly with other agents

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Cool and dry place
  • Protection from light
  • Keep out of the reach of children

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