Ometor 40 mg/vial (IV Injection)

40 mg vial: ৳ 80.00

Medicine Details

Category Details
Generic Omeprazole
Company Astra biopharmaceuticals ltd
Also available as

Title

  • Ometor

Categories

  • Medicine
  • Gastrointestinal Health

Description

  • Indicated for the treatment of gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer treatment
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Treatment of gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Treatment of acid-related dyspepsia
  • Treatment of severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Treatment of Zollinger-Ellison syndrome
  • Treatment of Helicobacter pylori-induced peptic ulcer
  • Inhibitor of gastric acid secretion
  • Onset of the antisecretory effect within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasting up to 72 hours
  • Discontinued drug results in gradual return of secretory activity over 3 to 5 days
  • Oral dosage form available
  • IV Injection dosage form available
  • Instructions for administration as IV Injection
  • Instructions for administration as IV Infusion
  • Pharmacological interaction with ketoconazole
  • Pharmacological interaction with cytochrome P450
  • Monitoring of patients receiving warfarin or phenytoin recommended
  • No change in blood concentration of phenytoin with concomitant treatment
  • No change in coagulation time in patients on continuous treatment with warfarin
  • Plasma concentrations of Ometor and clarithromycin increased during concomitant administration

Dimensions

  • N/A

Color Options

  • N/A

Functions

  • Inhibits gastric acid secretion
  • Treats various gastrointestinal disorders
  • Prophylaxis of acid aspiration
  • Helicobacter pylori eradication regimen
  • Management of severe ulcerating reflux esophagitis

Materials

  • Omeprazole
  • Substituted benzimidazole
  • H/K ATPase enzyme system inhibitor

Technical Specifications

  • 20 mg and 40 mg oral dosage strengths
  • IV Injection of 40 mg
  • Maximum IV Infusion period of 30 minutes
  • IV reconstitution with water for injection
  • IV reconstitution with saline for infusion or 5% Dextrose for infusion
  • Instructions for IV solution usage timeline

Design Elements

  • N/A

Usability Features

  • Well-tolerated with generally mild and reversible adverse reactions
  • Administration during pregnancy permissible based on epidemiological studies
  • The absence of information on the passage of Omeprazole into breast milk

Side Effects

  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia
  • Diarrhea and headache
  • Constipation, nausea/vomiting, flatulence, and abdominal pain
  • Dry mouth, stomatitis, and candidiasis
  • Paraesthesia
  • Dizziness, light headedness, and feeling faint
  • Somnolence, insomnia, and vertigo
  • Reversible mental confusion, agitation, depression, and hallucinations
  • Arthritic and myalgic symptoms
  • Blurred vision, taste disturbance, peripheral edema, and increased sweating
  • Gynaecomastia, leucopenia, thrombocytopenia, agranulocytosis, pancytopenia, and anaphylactic shock
  • Malaise, fever, bronchospasm, encephalopathy, hepatitis, interstitial nephritis, and hepatic failure
  • Increases in liver enzymes

Pregnancy & Lactation

  • Three prospective epidemiological studies indicate no adverse effects on pregnancy or the fetus/newborn child
  • Omeprazole can be used during pregnancy
  • No information available on the passage of Omeprazole into breast milk
  • Breastfeeding should be discontinued if essential use of Omeprazole is considered

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and Ometor
  • Proton pump inhibitor (PPI) therapy may be associated with an increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in gastric corpus biopsies from long-term Ometor use
  • Concomitant use of PPIs with methotrexate may lead to methotrexate toxicities

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

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