Maxima 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 7.00 (10 x 14: ৳ 980.00)
Strip Price: ৳ 98.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Acme laboratories ltd |
| Also available as |
Title
- Maxima 20 mg Tablet
Categories
- Proton Pump Inhibitor
- Gastrointestinal Medication
- Acid Reducer
Description
- Relieves heartburn
- Heals erosive esophagitis
- Treats GERD and related symptoms
- Eradicates Helicobacter pylori infection
- Manages Zollinger-Ellison Syndrome
- Addresses acid-related dyspepsia
- Aids in treating duodenal and gastric ulcers
DosageForms
- Oral tablet
- Oral suspension
- IV injection
- IV infusion
DosageStrengths
- 20 mg
- 40 mg
Indications
- Relief from chronic heartburn symptoms
- Erosive esophagitis healing
- Maintenance of erosive esophagitis healing
- Helicobacter pylori eradication in duodenal ulcer disease
- Treatment for Zollinger-Ellison Syndrome
- Management of acid-related dyspepsia
- Treatment for duodenal and gastric ulcers
Pharmacology
- Proton pump inhibitor
- Suppresses gastric acid secretion
- Enhances acid control
- Enteric-coated pellet formulation
- Peak plasma levels at approximately 1.5 hours after oral administration
- 97% bound to plasma proteins
- Metabolized by CYP enzymes
- Decreases gastric acid secretion
- Absorption affected by food intake
Contraindications
- Known hypersensitivity to any of the formulation
AdministrationInstructions
- Swallow whole one hour before a meal (tablet or capsule)
- Administer with water (oral suspension)
- Prepare solution with 0.9% Sodium Chloride for IV injection
- Administer IV injection over at least 3 minutes
Interaction
- Metabolized by CYP2C19 and CYP3A4 enzymes
- Unlikely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
- Potential interference with CYP2C19 substrate drugs
- Possible alteration of drug absorption due to gastric pH interference
- Plasma level increases in combination therapy with clarithromycin
SideEffects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
PregnancyAndLactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects in animal studies
- Excretion in milk not studied
- Discontinue breastfeeding if essential use is considered
PrecautionsAndWarnings
- Non-exclusion of gastric malignancy despite symptomatic response
- Instructions for patients with difficulty swallowing capsules
- Use of antacids while taking Maxima
UseInSpecialPopulations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety and efficacy observed between elderly and younger individuals
- No dosage adjustment recommended for mild to moderate hepatic insufficiency
- No alteration in pharmacokinetics for renal impairment
OverdoseEffects
- Lethal to rats at high doses
- Symptomatic and supportive treatment recommended in case of overdosage
StorageConditions
- Store at a temperature not exceeding 30°C
- Protect from light and moisture
- Keep out of reach of children
ChemicalStructure
- Molecular Formula: C17H19N3O3S
CommonQuestions
- Used for treating GERD, ulcers, and conditions involving excess stomach acid
- Common side effects include headache, diarrhea, nausea, and abdominal pain
- Considerations for pregnancy, breastfeeding, and long-term use
SpecialInstructions
- Applesauce mixing for patients with difficulty swallowing capsules
- Avoid eating late at night or before bedtime
- Consult doctor for potential side effects and concerns
TechnicalDetails
- Absorption affected by food intake
- Plasma protein binding is constant over a specific concentration range
- Metabolism dependent on CYP2C19 and CYP3A4 enzymes
- Extensive excretion as metabolites in urine and feces