Omsec 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (6 x 6: ৳ 252.00)
Strip Price: ৳ 42.00

Medicine Details

Category Details
Generic Omeprazole
Company Techno drugs ltd
Also available as
Omsec 20 mg capsule Omsec 40 mg injection

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasting up to 72 hours

Dosage

  • Dosage for benign gastric and duodenal ulcer
  • Dosage for NSAID-associated duodenal or gastric ulcer
  • Dosage for gastro-esophageal reflux disease
  • Dosage for long-term management of acid reflux disease
  • Dosage for acid-related dyspepsia
  • Dosage for prophylaxis of acid aspiration
  • Dosage for Zollinger-Ellison syndrome
  • Dosage for Helicobacter pylori eradication regimen in peptic ulcer disease
  • Pediatric use in severe ulcerating reflux esophagitis

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Reconstitution of IV injection
  • Reconstitution of IV infusion
  • Stability of reconstituted solution

Interaction

  • Impact on absorption of ketoconazole
  • Metabolism through cytochrome P450
  • Potential interaction with diazepam, phenytoin, and warfarin
  • Plasma concentration changes during concomitant administration

Contraindications

  • Known hypersensitivity to omeprazole
  • Suspected gastric ulcer with possibility of malignancy

Side Effects

  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, erythema multiforme, and angioedema
  • Diarrhea, headache, constipation, and nausea/vomiting
  • Gastrointestinal reactions
  • Dry mouth, stomatitis, and candidiasis
  • Neurological symptoms
  • Mental confusion, agitation, depression, and hallucinations
  • Arthritic and myalgic symptoms
  • Other rare adverse reactions

Pregnancy & Lactation

  • Effect on pregnancy and fetus/newborn child
  • Use during pregnancy
  • Passage into breast milk and effects on the neonate
  • Discontinuation of breastfeeding

Precautions & Warnings

  • Avoid concomitant use of clopidogrel
  • Possible association with increased risk of osteoporosis-related fractures
  • Occasional atrophic gastritis noted in long-term treatment
  • Potential interactions with methotrexate

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place
  • Away from light and heat
  • Keep out of the reach of children

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