Ampimet 500 mg (Capsule)
Unit Price: ৳ 5.00 (50's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ampicillin sodium |
| Company | Medimet pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of genitourinary tract infections including gonorrhea
- Treatment of respiratory tract infections
- Treatment of gastrointestinal tract infections
- Treatment of meningitis caused by N. meningitides
Pharmacology
- Inhibits bacterial cell wall synthesis
- Binds to penicillin-binding proteins
- Inhibits final transpeptidation step of peptidoglycan synthesis
- Causes bacterial lysis
Dosage
- Intra-articular
- Intraperitoneal
- Intrapleural
- Intravenous for meningitis
- Intravenous for intrapartum prophylaxis
- Oral for various infections
- Parenteral for susceptible infections
- Parenteral for septicaemia
Administration
Should be taken on an empty stomach
Interaction
- May reduce efficacy of oral contraceptives
- May alter INR while on warfarin and phenindione
- May reduce efficacy of oral typhoid vaccines
- May reduce excretion of methotrexate
- Reduced excretion with probenecid and sulfinpyrazone
- Allopurinol increases ampicillin-induced skin reactions
- Reduced absorption with chloroquine
- Interference with bactericidal action by bacteriostatic antibacterials
Contraindications
Hypersensitivity to ampicillin and other penicillins
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Rashes
- Sore mouth
- Rash
- Fever
- Joint pains
- Haemolytic anaemia
- Thrombocytopenia
- Leucopenia
- Neutropenia
- CNS toxicity
- Paraesthesia
- Nephropathy
- Hepatitis
- Cholestatic jaundice
- Anaphylaxis
Pregnancy & Lactation
Pregnancy Category B
Precautions & Warnings
- Patients with history of β-lactam allergy
- During renal impairment
- During pregnancy and lactation
Use in Special Populations
Dose reduction or increase in dose interval for renal impairment
Overdose Effects
- Nausea
- Vomiting
- Diarrhoea
Reconstitution
- Intramuscular reconstitution process
- Intravenous reconstitution process
- Intra-articular reconstitution process
- Intraperitoneal reconstitution process
- Intrapleural reconstitution process
Storage Conditions
Store between 20-25° C. Reconstituted oral suspension to be stored between 2-8° C and discarded after 14 days