Omaprin 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 4.00 (40's pack: ৳ 160.00)

Medicine Details

Category Details
Generic Omeprazole
Company Doctors chemical works ltd

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated ulcers
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase enzyme system
  • Onset of effect within one hour
  • Maximum effect within two hours
  • Effect lasting up to 72 hours

Dosage

  • Different dosages for various conditions
  • Maintenance doses for recurrent ulcers
  • Dosage adjustment for severe cases
  • Pediatric dosage based on body weight
  • Oral and IV administration options

Administration

  • IV Injection instructions
  • IV Infusion directions
  • Reconstitution guidelines
  • Slow intravenous injection recommended
  • Usage time frame for reconstituted solution

Interaction

  • Impact on ketoconazole absorption
  • Metabolism through cytochrome P450
  • Possible delay in elimination of certain drugs
  • Monitoring advised for warfarin and phenytoin
  • Plasma concentration changes with clarithromycin

Contraindications

  • Hypersensitivity to omeprazole
  • Exclusion of malignancy in gastric ulcer cases before treatment

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, pruritus reported
  • Photosensitivity and bullous eruption possible
  • Gastrointestinal reactions like diarrhea and nausea
  • Neurological symptoms like dizziness and somnolence

Pregnancy & Lactation

  • No adverse effects on pregnancy or fetus noted
  • Usage during pregnancy deemed safe
  • Discontinuation of breastfeeding suggested

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Increased risk of osteoporosis-related fractures
  • Atrophic gastritis potential with long-term use
  • Potential interactions with methotrexate

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Store in a dry place
  • Keep away from light and heat
  • Keep out of the reach of children

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