Omesil 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.75 (10 x 10: ৳ 575.00)
Strip Price: ৳ 57.50

Medicine Details

Category Details
Generic Omeprazole
Company Silva pharmaceuticals ltd
Also available as
Omesil fast 40 mg powder

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Acid reflux disease long-term management
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum effect within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Gradual return of secretory activity over 3 to 5 days after discontinuation

Dosage

  • Different dosages for various conditions like ulcers, reflux diseases, dyspepsia
  • Oral and IV injection dosing instructions
  • Maintenance doses for recurrent ulcers
  • Dosages for pediatric use in reflux esophagitis

Administration

  • Direction for IV injection use
  • Direction for IV infusion use
  • Reconstitution instructions
  • Usage timeline after reconstitution
  • Instructions for preparation and administration

Interaction

  • Interactions with ketoconazole, diazepam, phenytoin, warfarin
  • Monitoring of patients receiving warfarin or phenytoin
  • Induction of cytochrome P450 by Omesil

Contraindications

  • Known hypersensitivity to omeprazole
  • Exclusion of malignancy possibility before treatment initiation

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, pruritus
  • Photosensitivity, bullous eruption, erythema multiforme
  • Gastrointestinal reactions like diarrhea, headache, constipation
  • Neurological reactions like dizziness, vertigo, somnolence
  • Hematological reactions like leucopenia, thrombocytopenia, anemia

Pregnancy & Lactation

  • No adverse effects on pregnancy or fetus/newborn child reported
  • Safe to use during pregnancy
  • No information on passage into breast milk

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Possible association with increased risk for osteoporosis-related fractures
  • Atrophic gastritis in long-term users
  • Potential methotrexate toxicities with concomitant use

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

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