Ometid 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.00 (9 x 10: ৳ 540.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Omeprazole
Company Opsonin pharma ltd
Also available as
Ometid 40 mg capsule Ometid 40 mg injection

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasting up to 72 hours
  • Gradual return of secretory activity over 3 to 5 days upon discontinuation

Dosage

  • Dosage for benign gastric and duodenal ulcer
  • Dosage for NSAID-associated duodenal or gastric ulcer
  • Dosage for gastro-esophageal reflux disease
  • Dosage for long-term management of acid reflux disease
  • Dosage for acid-related dyspepsia
  • Dosage for prophylaxis of acid aspiration
  • Dosage for Zollinger-Ellison syndrome
  • Dosage for Helicobacter pylori eradication regimen in peptic ulcer disease
  • Pediatric dosage for severe ulcerating reflux esophagitis

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Instructions for reconstitution and administration of IV injection
  • Instructions for IV infusion preparation and administration
  • Caution for co-administration with other drugs in the same infusion set

Interaction

  • Effect on absorption of ketoconazole
  • Metabolism in the liver through cytochrome P450
  • Potential delay in the elimination of diazepam, phenytoin, and warfarin
  • Monitoring and dose adjustment recommendations for warfarin or phenytoin
  • Increased plasma concentrations during concomitant administration with clarithromycin
  • No evidence of interaction with certain drugs such as phenacetin, theophylline, caffeine, etc.

Contraindications

  • Known hypersensitivity to Omeprazole
  • Exclusion of malignancy before treatment in suspected gastric ulcer

Side Effects

  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, and erythema multiforme
  • Diarrhea and headache
  • Gastrointestinal reactions such as constipation, nausea/vomiting, flatulence, and abdominal pain
  • Neurological symptoms like paraesthesia, dizziness, and vertigo
  • Mental confusion, agitation, and depression
  • Musculoskeletal symptoms like arthritic and myalgic symptoms
  • Reports of blurred vision, taste disturbance, and peripheral edema
  • Hepatic reactions and increased liver enzymes

Pregnancy & Lactation

  • Results from prospective epidemiological studies
  • Use during pregnancy without observed adverse effects
  • No information available on passage into breast milk or effects on neonate
  • Recommendation for discontinuation of breastfeeding if essential use is considered

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and Ometid
  • Association between PPI therapy and increased risk for osteoporosis-related fractures
  • Occurrence of atrophic gastritis in long-term treatment
  • Potential for methotrexate toxicities with concomitant PPI use

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

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