Ometor 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 4.00 (6 x 10: ৳ 240.00)

Strip Price: ৳ 40.00

Medicine Details

Category	Details
Generic	Omeprazole
Company	Astra biopharmaceuticals ltd
Also available as	Ometor 40 mg injection

Gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

20 mg once daily for benign gastric and duodenal ulcer
40 mg daily in severe or recurrent cases
10-20 mg daily for prevention of relapse in duodenal ulcer
20 mg once daily for NSAID-associated duodenal or gastric ulcer for 4-8 weeks
40 mg once daily for gastro-esophageal reflux disease for 4-8 weeks
10-20 mg daily for long-term management of acid reflux disease
10-20 mg once daily for 2-4 weeks for acid-related dyspepsia
40 mg on the preceding evening, then 40 mg 2-6 hours before surgery for prophylaxis of acid aspiration
Initially 60 mg once daily for Zollinger-Ellison syndrome, usual range 20-120 mg daily
20 mg twice daily for Helicobacter pylori eradication regimen in peptic ulcer disease
10-20 mg once daily for 4-12 weeks for severe ulcerating reflux esophagitis (Child>1 year)

IV Injection for prophylaxis of acid aspiration
IV Infusion over 20-30 minutes
Slow intravenous injection over at least 2 to 5 minutes at a maximum rate of 4 ml/minute
Use within 4 hours of reconstitution for IV injection
Use within 12 hours when dissolved in saline and within 6 hours when dissolved in 5% Dextrose for IV infusion
Reconstituted solution should not be mixed or co-administered with any other drug

Decreased intragastric acidity may reduce the absorption of ketoconazole
Metabolized in the liver through cytochrome P450, can delay the elimination of diazepam, phenytoin and warfarin
Increased plasma concentrations during concomitant administration with clarithromycin for H. pylori eradication
No evidence of interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxycillin, antacids, alcohol or food

Known hypersensitivity to Omeprazole
Suspicion of gastric ulcer should exclude the possibility of malignancy before treatment

Skin rash, urticaria, pruritus
Photosensitivity, bullous eruption, erythema multiforme, angioedema, alopecia
Diarrhoea, headache
Gastrointestinal reactions: constipation, nausea/vomiting, flatulence, abdominal pain
Dry mouth, stomatitis, candidiasis
Paraesthesia, dizziness, lightheadedness, feeling faint
Somnolence, insomnia, vertigo
Reversible mental confusion, agitation, depression, hallucinations
Arthritic and myalgic symptoms
Blurred vision, taste disturbance, peripheral oedema, increased sweating, gynaecomastia
Leucopenia, thrombocytopenia, agranulocytosis, pancytopenia, anaphylactic shock, malaise, fever
Hepatic effects: hepatitis with or without jaundice, interstitial nephritis, hepatic failure

No adverse effects on pregnancy or on the health of the fetus/newborn child in three prospective epidemiological studies
Use during pregnancy considered safe
No information available on the passage of Omeprazole into breast milk or its effects on the neonate
Breast-feeding should be discontinued if Omeprazole use is considered essential

Avoid concomitant use with clopidogrel
PPI therapy may be associated with an increased risk for osteoporosis-related fractures
Atrophic gastritis noted occasionally in patients treated long-term
Concomitant use with methotrexate may lead to methotrexate toxicities