Seloktil 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Belsen pharmaceuticals ltd |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocker of hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of anti-secretory effect within one hour
- Maximum effect occurring within two hours
Dosage
- Dosage for gastric and duodenal ulcer
- Dosage for NSAID-associated duodenal or gastric ulcer
- Dosage for gastro-esophageal reflux disease
- Dosage for long-term management of acid reflux disease
- Dosage for acid-related dyspepsia
- Dosage for prophylaxis of acid aspiration
- Dosage for Zollinger-Ellison syndrome
- Dosage for Helicobacter pylori eradication regimen
Administration
- Direction for use of IV injection
- Direction for use of IV infusion
- Reconstitution instructions for IV injection
- Reconstitution instructions for IV infusion
Interaction
- Potential interaction with ketoconazole absorption
- Metabolism through cytochrome P450
- Monitoring for warfarin and phenytoin
- Interaction with clarithromycin during H. pylori eradication
- No evidence of interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxicillin or antacids
Contraindications
- Known hypersensitivity
- Suspected gastric ulcer with possibility of malignancy
Side Effects
- Skin rash
- Urticaria
- Pruritus
- Diarrhoea
- Headache
- Nausea/vomiting
- Flatulence
- Abdominal pain
- Dry mouth
- Stomatitis
- Candidiasis
- Paraesthesia
- Dizziness
- Light headedness
- Somnolence
- Insomnia
- Vertigo
- Mental confusion
- Agitation
- Depression
- Hallucinations
- Arthritic symptoms
- Myalgic symptoms
- Blurred vision
- Taste disturbance
- Peripheral oedema
- Increased sweating
- Gynaecomastia
- Leucopenia
- Thrombocytopenia
- Agranulocytosis
- Pancytopenia
- Anaphylactic shock
- Malaise
- Fever
- Bronchospasm
- Encephalopathy in patients with pre-existing severe liver disease
- Hepatitis
- Interstitial nephritis
- Hepatic failure
- Increases in liver enzymes
Pregnancy & Lactation
- No adverse effects on pregnancy
- No adverse effects on the health of the fetus/newborn child
- Use during pregnancy
- Lack of information on passage into breast milk
- Necessity to discontinue breastfeeding if essential
Precautions & Warnings
- Avoid concomitant use of clopidogrel
- Association with increased risk for osteoporosis-related fractures
- Potential atrophic gastritis in long-term use
- Potential methotrexate toxicities in concomitant use
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
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