Seloktil 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Omeprazole
Company Belsen pharmaceuticals ltd

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocker of hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of anti-secretory effect within one hour
  • Maximum effect occurring within two hours

Dosage

  • Dosage for gastric and duodenal ulcer
  • Dosage for NSAID-associated duodenal or gastric ulcer
  • Dosage for gastro-esophageal reflux disease
  • Dosage for long-term management of acid reflux disease
  • Dosage for acid-related dyspepsia
  • Dosage for prophylaxis of acid aspiration
  • Dosage for Zollinger-Ellison syndrome
  • Dosage for Helicobacter pylori eradication regimen

Administration

  • Direction for use of IV injection
  • Direction for use of IV infusion
  • Reconstitution instructions for IV injection
  • Reconstitution instructions for IV infusion

Interaction

  • Potential interaction with ketoconazole absorption
  • Metabolism through cytochrome P450
  • Monitoring for warfarin and phenytoin
  • Interaction with clarithromycin during H. pylori eradication
  • No evidence of interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxicillin or antacids

Contraindications

  • Known hypersensitivity
  • Suspected gastric ulcer with possibility of malignancy

Side Effects

  • Skin rash
  • Urticaria
  • Pruritus
  • Diarrhoea
  • Headache
  • Nausea/vomiting
  • Flatulence
  • Abdominal pain
  • Dry mouth
  • Stomatitis
  • Candidiasis
  • Paraesthesia
  • Dizziness
  • Light headedness
  • Somnolence
  • Insomnia
  • Vertigo
  • Mental confusion
  • Agitation
  • Depression
  • Hallucinations
  • Arthritic symptoms
  • Myalgic symptoms
  • Blurred vision
  • Taste disturbance
  • Peripheral oedema
  • Increased sweating
  • Gynaecomastia
  • Leucopenia
  • Thrombocytopenia
  • Agranulocytosis
  • Pancytopenia
  • Anaphylactic shock
  • Malaise
  • Fever
  • Bronchospasm
  • Encephalopathy in patients with pre-existing severe liver disease
  • Hepatitis
  • Interstitial nephritis
  • Hepatic failure
  • Increases in liver enzymes

Pregnancy & Lactation

  • No adverse effects on pregnancy
  • No adverse effects on the health of the fetus/newborn child
  • Use during pregnancy
  • Lack of information on passage into breast milk
  • Necessity to discontinue breastfeeding if essential

Precautions & Warnings

  • Avoid concomitant use of clopidogrel
  • Association with increased risk for osteoporosis-related fractures
  • Potential atrophic gastritis in long-term use
  • Potential methotrexate toxicities in concomitant use

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

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