Osyn-20 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 4.00 (60's pack: ৳ 240.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Mst pharma |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
Inhibitor of gastric acid secretion
Dosage
- 20 mg once daily for benign gastric and duodenal ulcer
- 20 mg once daily for NSAID-associated duodenal or gastric ulcer
- 20 mg once daily for gastro-esophageal reflux disease
- 10-20 mg daily for long-term management of acid reflux disease
- 10-20 mg once daily for acid-related dyspepsia
- 40 mg on the preceding evening for prophylaxis of acid aspiration
Route of Administration
- Oral
- Intravenous
Interaction
- Decreased absorption of ketoconazole
- Delayed elimination of diazepam, phenytoin, and warfarin
- Increased plasma concentrations of Osyn-20 and clarithromycin
- No interaction with phenacetin, theophylline, caffeine, propranolol, etc.
- Increased bioavailability of digoxin
Contraindications
- Known hypersensitivity to omeprazole
- Suspected gastric ulcer with possibility of malignancy
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, pruritus, photosensitivity
- Diarrhea, headache, constipation, nausea/vomiting
- Dry mouth, stomatitis, paraesthesia, dizziness
- Arthritic and myalgic symptoms
- Blurred vision, taste disturbance, peripheral edema
- Liver enzyme increases
Pregnancy & Lactation
- No adverse effects on pregnancy or fetus/child health
- Can be used during pregnancy
- No information on passage into breast milk
- Discontinue breastfeeding if Omeprazole essential
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Increased risk for osteoporosis-related fractures
- Atrophic gastritis with long-term use
- Methotrexate toxicities
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep in a dry place away from light and heat