Esoprex 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (10 x 10: ৳ 800.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Esomeprazole
Company Beacon pharmaceuticals plc
Also available as
Esoprex 40 mg capsule Esoprex 40 mg injection

Title

Esoprex 20 mg Capsule

Categories

  • Medicine
  • Proton Pump Inhibitor
  • Gastrointestinal Health
  • Treatment
  • Pharmacology

Description

Esoprex 20 mg Capsule is a prescription medication used to treat chronic heartburn symptoms, GERD, erosive esophagitis, Helicobacter pylori infection, Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal and gastric ulcers. It belongs to the class of drugs known as proton pump inhibitors (PPIs), which work by reducing the amount of acid produced in the stomach.

Attributes

  • Indications:
    • Relieving chronic heartburn symptoms
    • Healing of erosive esophagitis
    • Maintenance of healing of erosive esophagitis
    • Eradication of Helicobacter pylori infection
    • Treating Zollinger-Ellison Syndrome
    • Managing acid-related Dyspepsia
    • Treatment of duodenal and gastric ulcers
  • Pharmacology:
    • Suppresses gastric acid secretion
    • First single optical isomer of proton pump inhibitor
    • Better acid control than racemic proton pump inhibitors
    • Absorbed via enteric-coated pellet formulation
    • Peak plasma levels occur at approximately 1.5 hours after oral administration
  • Dosage:
    • Various dosage regimens based on specific conditions
    • Oral dosing for healing and maintenance of erosive esophagitis, symptomatic GERD, Helicobacter pylori eradication, Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal and gastric ulcers
    • IV injection or infusion for certain conditions and age groups
  • Administration:
    • Tablets or capsules should be swallowed whole and taken one hour before a meal
    • Oral suspension should be prepared and administered as per instructions
    • IV injection requires specific reconstitution and administration guidelines
  • Interaction:
    • Metabolized in the liver by CYP2C19 and CYP3A4
    • Unlikely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
    • Potential interference with CYP2C19 and gastric pH-dependent drug absorption
    • No clinically significant interactions with specific drugs
  • Contraindications:
    • Known hypersensitivity to any of the formulation
  • Side Effects:
    • Headache
    • Diarrhoea
    • Nausea
    • Flatulence
    • Abdominal pain
    • Constipation
    • Dry mouth
  • Pregnancy & Lactation:
    • No adequate and well-controlled studies in pregnant women
    • No teratogenic effects in animal studies
    • Excretion in milk not studied
  • Precautions & Warnings:
    • Symptomatic response to therapy does not preclude the presence of gastric malignancy
    • Specific guidance for patients with difficulty swallowing capsules
  • Use in Special Populations:
    • Safety and effectiveness in paediatric patients not established
    • No overall differences in safety and efficacy in the elderly
    • No dosage adjustment for mild to moderate hepatic insufficiency
    • No alteration in pharmacokinetics in renal impairment
  • Overdose Effects:
    • Lethal at high doses in animal studies
    • No specific antidote known
    • Supportive and symptomatic treatment recommended
  • Storage Conditions:
    • Temperature not exceeding 30°C
    • Dry place
    • Protection from light and moisture
    • Keep out of reach of children
  • Chemical Structure:
    • Molecular Formula: C17H19N3O3S
    • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg
  • Common Questions:
    • What is Esoprex 20 mg Capsule?
    • What is it used for?
    • What are the side effects?
    • Can it be taken during pregnancy or breastfeeding?
    • How long does it take to work?

Related Brands