Omepra 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 4.01 (10 x 10: ৳ 401.00)
Strip Price: ৳ 40.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Alco pharma ltd |
| Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect occurs within one hour
- Maximum effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
Dosage
- Oral administration
- Dosage for gastric and duodenal ulcer
- Dosage for NSAID-associated duodenal or gastric ulcer
- Dosage for gastro-esophageal reflux disease
- Dosage for long-term management of acid reflux disease
- Dosage for acid-related dyspepsia
- Dosage for prophylaxis of acid aspiration
- Dosage for Zollinger-Ellison syndrome
- Pediatric dosage for severe ulcerating reflux esophagitis
- IV Injection for prophylaxis of acid aspiration
- IV Injection for duodenal ulcer, gastric ulcer or reflux esophagitis
- IV Injection for Zollinger-Ellison syndrome (ZES)
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
Interaction
- Decreased intragastric acidity affecting ketoconazole absorption
- Metabolism through cytochrome P450 affecting diazepam, phenytoin, and warfarin elimination
- Plasma concentrations increased during concomitant administration
Contraindications
- Known hypersensitivity to omeprazole
- Suspicion of gastric ulcer with possibility of malignancy
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, and pruritus
- Photosensitivity, bullous eruption, and erythema multiforme
- Diarrhea and headache
- Gastrointestinal reactions
- Dry mouth, stomatitis, and candidiasis
- Paraesthesia and dizziness
- Reversible mental confusion, agitation, and depression
- Arthritic and myalgic symptoms
- Blurred vision, taste disturbance, and peripheral edema
Pregnancy & Lactation
- No adverse effects on pregnancy or fetus/newborn child
- Use during pregnancy
- No information on passage into breast milk
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Increased risk for osteoporosis-related fractures
- Atrophic gastritis with long-term use
- Concomitant use with methotrexate leading to toxicities
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children