Omepra 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 4.01 (10 x 10: ৳ 401.00)
Strip Price: ৳ 40.10

Medicine Details

Category Details
Generic Omeprazole
Company Alco pharma ltd
Also available as
Omepra 40 mg capsule

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect occurs within one hour
  • Maximum effect occurs within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Oral administration
  • Dosage for gastric and duodenal ulcer
  • Dosage for NSAID-associated duodenal or gastric ulcer
  • Dosage for gastro-esophageal reflux disease
  • Dosage for long-term management of acid reflux disease
  • Dosage for acid-related dyspepsia
  • Dosage for prophylaxis of acid aspiration
  • Dosage for Zollinger-Ellison syndrome
  • Pediatric dosage for severe ulcerating reflux esophagitis
  • IV Injection for prophylaxis of acid aspiration
  • IV Injection for duodenal ulcer, gastric ulcer or reflux esophagitis
  • IV Injection for Zollinger-Ellison syndrome (ZES)

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion

Interaction

  • Decreased intragastric acidity affecting ketoconazole absorption
  • Metabolism through cytochrome P450 affecting diazepam, phenytoin, and warfarin elimination
  • Plasma concentrations increased during concomitant administration

Contraindications

  • Known hypersensitivity to omeprazole
  • Suspicion of gastric ulcer with possibility of malignancy

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, and erythema multiforme
  • Diarrhea and headache
  • Gastrointestinal reactions
  • Dry mouth, stomatitis, and candidiasis
  • Paraesthesia and dizziness
  • Reversible mental confusion, agitation, and depression
  • Arthritic and myalgic symptoms
  • Blurred vision, taste disturbance, and peripheral edema

Pregnancy & Lactation

  • No adverse effects on pregnancy or fetus/newborn child
  • Use during pregnancy
  • No information on passage into breast milk

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Increased risk for osteoporosis-related fractures
  • Atrophic gastritis with long-term use
  • Concomitant use with methotrexate leading to toxicities

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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