Prevas 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Omeprazole
Company General pharmaceuticals ltd
Also available as
Prevas 40 mg capsule Prevas 40 mg injection

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of the antisecretory effect occurs within one hour
  • Maximum effect occurs within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Dosage available for benign gastric and duodenal ulcer
  • Dosage available for NSAID-associated duodenal or gastric ulcer
  • Dosage available for gastro-esophageal reflux disease
  • Dosage available for long-term management of acid reflux disease
  • Dosage available for acid-related dyspepsia
  • Dosage available for prophylaxis of acid aspiration
  • Dosage available for Zollinger-Ellison syndrome
  • Dosage available for Helicobacter pylori eradication regimen in peptic ulcer disease
  • Pediatric use in severe ulcerating reflux esophagitis

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • IV injection should be given as a slow intravenous injection
  • IV infusion should be given as an intravenous infusion over a period of 20-30 minutes or more

Interaction

  • Decreased intragastric acidity
  • Absorption of ketoconazole may be reduced
  • Metabolized in the liver through cytochrome P450
  • Plasma concentrations of Prevas and clarithromycin are increased during concomitant administration
  • No evidence of an interaction with piroxicam, diclofenac, or naproxen

Contraindications

  • Known hypersensitivity to Omeprazole
  • Possibility of malignancy when gastric ulcer is suspected

Side Effects

  • Skin rash, urticaria and pruritus
  • Photosensitivity, bullous eruption, erythema multiforme, angioedema and alopecia
  • Diarrhea and headache
  • Gastrointestinal reactions like constipation, nausea/vomiting, flatulence and abdominal pain
  • Dry mouth, stomatitis and candidiasis
  • Paraesthesia
  • Dizziness, light headedness
  • Reversible mental confusion, agitation, depression and hallucinations
  • Arthritic and myalgic symptoms
  • Blurred vision, taste disturbance, peripheral oedema

Pregnancy & Lactation

  • No adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child
  • Omeprazole can be used during pregnancy

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and Prevas
  • Proton pump inhibitor (PPI) therapy may be associated with an increased risk for osteoporosis-related fractures
  • Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with Prevas
  • Concomitant use of PPIs with methotrexate may lead to methotrexate toxicities

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Related Brands