Propin 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.01 (40's pack: ৳ 200.40)

Medicine Details

Category Details
Generic Omeprazole
Company Hallmark pharmaceuticals ltd
Also available as
Propin 40 mg capsule

Indications

  • Treatment of gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer treatment
  • Prophylaxis in patients with history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease treatment
  • Long-term management of acid reflux disease
  • Treatment of acid-related dyspepsia
  • Severe ulcerating reflux esophagitis treatment
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome treatment
  • Helicobacter pylori-induced peptic ulcer treatment

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum antisecretory effect within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Oral administration for various conditions and maintenance doses
  • IV Injection for prophylaxis of acid aspiration and specific syndromes
  • Different dosages for severe ulcerating reflux esophagitis in paediatric use

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Preparation of IV infusion solution
  • Instructions for slow intravenous injection

Interaction

  • Absorption of ketoconazole may be reduced during treatment
  • Metabolised in the liver through cytochrome P450
  • Delay in elimination of diazepam, phenytoin, and warfarin
  • Monitoring of patients receiving warfarin or phenytoin
  • Plasma concentrations may be increased during concomitant administration

Contraindications

  • Known hypersensitivity to omeprazole
  • Exclusion of malignancy possibility before treatment

Side Effects

  • Mild and reversible adverse reactions
  • Reported skin rash, urticaria, and pruritus
  • Diarrhoea and headache reported
  • Gastrointestinal reactions included constipation, nausea/vomiting
  • Dizziness, light headedness, and feeling faint associated with treatment
  • Reversible mental confusion, agitation, depression, and hallucinations

Pregnancy & Lactation

  • No adverse effects of omeprazole on pregnancy or fetus
  • Use during pregnancy indicated
  • No information available on passage into breast milk
  • Breast-feeding discontinuation if essential use of omeprazole

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and omeprazole
  • Possible increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in patients treated long-term with omeprazole

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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