Esonix 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 7.00 (5 x 14: ৳ 490.00)
Strip Price: ৳ 98.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Relief from chronic heartburn symptoms and other symptoms associated with GERD
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease in combination with amoxicillin and clarithromycin
- Zollinger-Ellison Syndrome
- Acid-related Dyspepsia
- Duodenal & Gastric ulcer
Pharmacology
- Suppresses gastric acid secretion
- Inhibits the H+/K+-ATPase in the gastric parietal cell
- Improves acid control
- Enteric-coated pellet formulation for capsules
- Peak plasma levels occur at approximately 1.5 hours after oral administration
- Metabolized in the liver by the cytochrome P450 (CYP) enzyme system
- Plasma elimination half-life is approximately 1–1.5 hours
- Combination therapy with antimicrobials
Dosage
- Oral dosage form for various indications
- IV Injection or IV infusion for specific conditions
- Different doses for adult and pediatric patients
- Duration of treatment for different indications
Administration
- Tablet or capsule should be swallowed whole
- Oral Suspension administration instructions
- IV Injection preparation and administration
Interaction
- Metabolized in the liver by CYP2C19 and CYP3A4
- Potential interference with CYP2C19
- Possible interactions with drugs metabolized by CYP enzymes
- Impact on absorption of certain drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Animal studies show no teratogenic effects
- Excretion in milk not studied
- Breastfeeding discontinuation if essential
Precautions & Warnings
- Symptomatic response to therapy does not preclude the presence of gastric malignancy
- Special instructions for administering capsules to patients with swallowing difficulties
- Use of antacids while taking the medication
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- No overall differences in safety and efficacy observed between the elderly and younger individuals
- No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
- Pharmacokinetics in patients with renal impairment
Overdose Effects
- Signs of acute toxicity in animal studies
- No specific antidote known
- Symptomatic and supportive treatment recommended
Storage Conditions
- Temperature not exceeding 30°C
- Protection from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image
Common Questions about Esonix 20 mg Tablet
- Mechanism of action
- Uses of Esonix 20 mg Tablet
- Common side effects
- Pregnancy and breastfeeding precautions
- Onset of action
- Quick Tips for patients