Maxima 40 mg/vial (IV Injection)

40 mg vial: ৳ 90.27

Medicine Details

Category Details
Generic Esomeprazole
Company Acme laboratories ltd
Also available as
Maxima 20 mg capsule Maxima 40 mg capsule Maxima 20 mg tablet Maxima 40 mg tablet

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid-related Dyspepsia
  • Treatment of Duodenal and Gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Inhibition of H+/K+-ATPase
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation
  • Peak plasma levels at approximately 1.5 hours
  • Metabolized in the liver by CYP enzyme system
  • Excretion in urine and faeces

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Specific dosage for healing of erosive esophagitis
  • Specific dosage for symptomatic GERD
  • Specific dosage for Helicobacter pylori eradication
  • Specific dosage for Zollinger-Ellison Syndrome
  • Specific dosage for Acid-related Dyspepsia
  • Specific dosage for Duodenal and Gastric ulcers
  • Dosage for pediatric and adult patients
  • Dosage for risk reduction of rebleeding of ulcers

Administration

  • Tablet or capsule administration
  • Oral suspension administration
  • IV Injection solution preparation
  • IV Injection administration
  • Instructions for administering through nasogastric or gastric tube

Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • Inhibition of CYP2C19
  • Potential interference with drug absorption
  • Lack of clinically significant interactions with certain drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied
  • Discontinuation of breast-feeding if essential

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Instructions for patients
  • Use of antacids while taking the product

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy in geriatric use
  • No dosage adjustment for mild to moderate hepatic insufficiency
  • No alteration of Pharmacokinetics in renal impairment

Overdose Effects

  • Lethal to rats at high doses
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Temperature not exceeding 30°C
  • Dry place
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Common Questions about Maxima 40 mg/vial Injection

  • Definition of Maxima 40 mg/vial Injection
  • Uses of Maxima 40 mg/vial Injection
  • Side effects of Maxima 40 mg/vial Injection
  • Safety during pregnancy and breastfeeding
  • Onset of action and quick tips

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